doi: 10.1001/jama.2022.21383.
Target Trial Emulation: A Framework for Causal Inference From Observational Data
Affiliations
- PMID: 36508210
- DOI: 10.1001/jama.2022.21383
Item in Clipboard
Target Trial Emulation: A Framework for Causal Inference From Observational Data
JAMA.
.
No abstract available
Plain language summary
This Guide to Statistics and Methods describes the use of target trial emulation to design an observational study so it preserves the advantages of a randomized clinical trial, points out the limitations of the method, and provides an example of its use.
Similar articles
-
Improving rheumatoid arthritis comparative effectiveness research through causal inference principles: systematic review using a target trial emulation framework.Ann Rheum Dis. 2020 Jul;79(7):883-890. doi: 10.1136/annrheumdis-2020-217200. Epub 2020 May 7. Ann Rheum Dis. 2020. PMID: 32381560 Free PMC article.
-
Designing observational studies for credible causal inference in addiction research-Directed acyclic graphs, modified disjunctive cause criterion and target trial emulation.Addiction. 2024 Jun;119(6):1125-1134. doi: 10.1111/add.16442. Epub 2024 Feb 11. Addiction. 2024. PMID: 38343103
-
Target Trial Emulation to Improve Causal Inference from Observational Data: What, Why, and How?J Am Soc Nephrol. 2023 Aug 1;34(8):1305-1314. doi: 10.1681/ASN.0000000000000152. Epub 2023 May 3. J Am Soc Nephrol. 2023. PMID: 37131279 Free PMC article. Review.
-
[Designing observational studies by target trial emulation].Ned Tijdschr Geneeskd. 2023 Nov 8;167:D7702. Ned Tijdschr Geneeskd. 2023. PMID: 37994775 Dutch.
-
Implementation of the trial emulation approach in medical research: a scoping review.BMC Med Res Methodol. 2023 Aug 16;23(1):186. doi: 10.1186/s12874-023-02000-9. BMC Med Res Methodol. 2023. PMID: 37587484 Free PMC article. Review.
Cited by
-
Infection prophylaxis among patients with antineutrophil cytoplasmic antibody (ANCA) vasculitis: a scoping review.Clin Rheumatol. 2024 Sep;43(9):2765-2781. doi: 10.1007/s10067-024-07074-4. Epub 2024 Jul 25. Clin Rheumatol. 2024. PMID: 39058400 Review.
-
Short- and long-term impact of aspirin cessation in older adults: a target trial emulation.BMC Med. 2024 Jul 29;22(1):306. doi: 10.1186/s12916-024-03507-8. BMC Med. 2024. PMID: 39075484 Free PMC article. Clinical Trial.
-
Impact of special educational needs provision on hospital utilisation, school attainment and absences for children in English primary schools stratified by gestational age at birth: A target trial emulation study protocol.NIHR Open Res. 2023 Nov 21;3:59. doi: 10.3310/nihropenres.13471.1. eCollection 2023. NIHR Open Res. 2023. PMID: 39139276 Free PMC article.
-
Optimal timing of nirmatrelvir/ritonavir treatment after COVID-19 symptom onset or diagnosis: target trial emulation.Nat Commun. 2023 Dec 16;14(1):8377. doi: 10.1038/s41467-023-43706-0. Nat Commun. 2023. PMID: 38104114 Free PMC article.
-
Morbidity and mortality risks associated with valproate withdrawal in young adults with epilepsy.Brain. 2024 Oct 3;147(10):3426-3441. doi: 10.1093/brain/awae128. Brain. 2024. PMID: 38657115 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
