Fatty acid desaturases (FADs) modulate multiple lipid metabolism pathways to improve plant resistance

doi:10.1007/s11033-022-07568-x

Review

. 2022 Oct;49(10):9997-10011.

doi: 10.1007/s11033-022-07568-x. Epub 2022 Jul 11.

Fatty acid desaturases (FADs) modulate multiple lipid metabolism pathways to improve plant resistance

Ruixue Xiao^#^{1

2

3}, Yirong Zou^#³, Xiaorui Guo^#³, Hui Li^{1

2

3}, Hai Lu^{4

5

6}

Affiliations

¹ National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, 100083, China.
² Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, Beijing Forestry University, Beijing, 100083, China.
³ The Tree and Ornamental Plant Breeding and Biotechnology Laboratory of National Forestry and Grassland Administration, College of Biological Sciences and Biotechnology, Beijing Forestry University, Tsinghua East Road 35, Haidian District, Beijing, 100083, China.
⁴ National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, 100083, China. luhai1974@bjfu.edu.cn.
⁵ Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, Beijing Forestry University, Beijing, 100083, China. luhai1974@bjfu.edu.cn.
⁶ The Tree and Ornamental Plant Breeding and Biotechnology Laboratory of National Forestry and Grassland Administration, College of Biological Sciences and Biotechnology, Beijing Forestry University, Tsinghua East Road 35, Haidian District, Beijing, 100083, China. luhai1974@bjfu.edu.cn.

^# Contributed equally.

PMID: 35819557
DOI: 10.1007/s11033-022-07568-x

Review

Fatty acid desaturases (FADs) modulate multiple lipid metabolism pathways to improve plant resistance

Ruixue Xiao et al. Mol Biol Rep. 2022 Oct.

. 2022 Oct;49(10):9997-10011.

doi: 10.1007/s11033-022-07568-x. Epub 2022 Jul 11.

Authors

Ruixue Xiao^#^{1

2

3}, Yirong Zou^#³, Xiaorui Guo^#³, Hui Li^{1

2

3}, Hai Lu^{4

5

6}

Affiliations

¹ National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, 100083, China.
² Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, Beijing Forestry University, Beijing, 100083, China.
³ The Tree and Ornamental Plant Breeding and Biotechnology Laboratory of National Forestry and Grassland Administration, College of Biological Sciences and Biotechnology, Beijing Forestry University, Tsinghua East Road 35, Haidian District, Beijing, 100083, China.
⁴ National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, 100083, China. luhai1974@bjfu.edu.cn.
⁵ Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, Beijing Forestry University, Beijing, 100083, China. luhai1974@bjfu.edu.cn.
⁶ The Tree and Ornamental Plant Breeding and Biotechnology Laboratory of National Forestry and Grassland Administration, College of Biological Sciences and Biotechnology, Beijing Forestry University, Tsinghua East Road 35, Haidian District, Beijing, 100083, China. luhai1974@bjfu.edu.cn.

^# Contributed equally.

PMID: 35819557
DOI: 10.1007/s11033-022-07568-x

Abstract

Background: Biological and abiotic stresses such as salt, extreme temperatures, and pests and diseases place major constraints on plant growth and crop yields. Fatty acids (FAs) and FA- derivatives are unique biologically active substance that show a wide range of functions in biological systems. They are not only participated in the regulation of energy storage substances and cell membrane plasm composition, but also extensively participate in the regulation of plant basic immunity, effector induced resistance and systemic resistance and other defense pathways, thereby improving plant resistance to adversity stress. Fatty acid desaturases (FADs) is involved in the desaturation of fatty acids, where desaturated fatty acids can be used as substrates for FA-derivatives.

Objective: In this paper, the role of omega-FADs (ω-3 FADs and ω-6 FADs) in the prokaryotic and eukaryotic pathways of fatty acid biosynthesis in plant defense against stress (biological and abiotic stress) and the latest research progress were summarized. Moreover' the existing problems in related research and future research directions were also discussed.

Results: Fatty acid desaturases are involved in various responses of plants during biotic and abiotic stress. For example, it is involved in regulating the stability and fluidity of cell membranes, reactive oxygen species signaling pathways, etc. In this review, we have collected several experimental studies to represent the differential effects of fatty acid desaturases on biotic and abiotic species.

Conclusion: Fatty acid desaturases play an important role in regulating biotic and abiotic stresses.

Keywords: Abiotic stress; Biotic stress; Eukaryotic pathway; Fatty acid desaturase; Prokaryotic pathway.

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References

1. Ohlrogge J, Browse J (1995) Lipid biosynthesis. Plant Cell 7(7):957–970. https://doi.org/10.2307/3870050 - DOI - PubMed - PMC
1. Lim GH, Singhal R, Kachroo A, Kachroo P (2017) Fatty acid- and lipid-mediated signaling in plant defense. Annu Rev Phytopathol 55:505–536. https://doi.org/10.1146/annurev-phyto-080516-035406 - DOI - PubMed
1. He M, Qin CX, Wang X, Ding NZ (2020) Plant unsaturated fatty acids: Biosynthesis and regulation. Front Plant Sci 11:390. https://doi.org/10.3389/fpls.2020.00390 - DOI - PubMed - PMC
1. Xue Y, Chen B, Win AN, Fu C, Lian J, Liu X, Wang R, Zhang X, Chai Y (2018) Omega-3 fatty acid desaturase gene family from two omega-3 sources, Salvia hispanica and Perilla frutescens: Cloning, characterization and expression. PLoS ONE 13(1):e0191432. https://doi.org/10.1371/journal.pone.0191432 - DOI - PubMed - PMC
1. Jusoh M, Loh SH, Chuah TS, Aziz A, Cha TS (2015) Indole-3-acetic acid (IAA) induced changes in oil content, fatty acid profiles and expression of four fatty acid biosynthetic genes in Chlorella vulgaris at early stationary growth phase. Phytochemistry 111:65–71. https://doi.org/10.1016/j.phytochem.2014.12.022 - DOI - PubMed

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[1] Ohlrogge J, Browse J (1995) Lipid biosynthesis. Plant Cell 7(7):957–970. https://doi.org/10.2307/3870050 - DOI - PubMed - PMC

[2] Ohlrogge J, Browse J (1995) Lipid biosynthesis. Plant Cell 7(7):957–970. https://doi.org/10.2307/3870050 - DOI - PubMed - PMC

[3] Lim GH, Singhal R, Kachroo A, Kachroo P (2017) Fatty acid- and lipid-mediated signaling in plant defense. Annu Rev Phytopathol 55:505–536. https://doi.org/10.1146/annurev-phyto-080516-035406 - DOI - PubMed

[4] Lim GH, Singhal R, Kachroo A, Kachroo P (2017) Fatty acid- and lipid-mediated signaling in plant defense. Annu Rev Phytopathol 55:505–536. https://doi.org/10.1146/annurev-phyto-080516-035406 - DOI - PubMed

[5] He M, Qin CX, Wang X, Ding NZ (2020) Plant unsaturated fatty acids: Biosynthesis and regulation. Front Plant Sci 11:390. https://doi.org/10.3389/fpls.2020.00390 - DOI - PubMed - PMC

[6] He M, Qin CX, Wang X, Ding NZ (2020) Plant unsaturated fatty acids: Biosynthesis and regulation. Front Plant Sci 11:390. https://doi.org/10.3389/fpls.2020.00390 - DOI - PubMed - PMC

[7] Xue Y, Chen B, Win AN, Fu C, Lian J, Liu X, Wang R, Zhang X, Chai Y (2018) Omega-3 fatty acid desaturase gene family from two omega-3 sources, Salvia hispanica and Perilla frutescens: Cloning, characterization and expression. PLoS ONE 13(1):e0191432. https://doi.org/10.1371/journal.pone.0191432 - DOI - PubMed - PMC

[8] Xue Y, Chen B, Win AN, Fu C, Lian J, Liu X, Wang R, Zhang X, Chai Y (2018) Omega-3 fatty acid desaturase gene family from two omega-3 sources, Salvia hispanica and Perilla frutescens: Cloning, characterization and expression. PLoS ONE 13(1):e0191432. https://doi.org/10.1371/journal.pone.0191432 - DOI - PubMed - PMC

[9] Jusoh M, Loh SH, Chuah TS, Aziz A, Cha TS (2015) Indole-3-acetic acid (IAA) induced changes in oil content, fatty acid profiles and expression of four fatty acid biosynthetic genes in Chlorella vulgaris at early stationary growth phase. Phytochemistry 111:65–71. https://doi.org/10.1016/j.phytochem.2014.12.022 - DOI - PubMed

[10] Jusoh M, Loh SH, Chuah TS, Aziz A, Cha TS (2015) Indole-3-acetic acid (IAA) induced changes in oil content, fatty acid profiles and expression of four fatty acid biosynthetic genes in Chlorella vulgaris at early stationary growth phase. Phytochemistry 111:65–71. https://doi.org/10.1016/j.phytochem.2014.12.022 - DOI - PubMed

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Fatty acid desaturases (FADs) modulate multiple lipid metabolism pathways to improve plant resistance

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Fatty acid desaturases (FADs) modulate multiple lipid metabolism pathways to improve plant resistance

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