Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Oct 15:214:114500.
doi: 10.1016/j.bios.2022.114500. Epub 2022 Jun 24.

A photoelectrochemical immunosensor based on Z-scheme CdS composite heterojunction for aflatoxin B1

Fubin Pei  1 , Shasha Feng  1 , Yuehua Zhang  2 , Yi Wu  1 , Chenglong Chen  1 , Yue Sun  1 , Zihao Xie  1 , Qingli Hao  1 , Yang Cao  1 , Zhaoyang Tong  3 , Wu Lei  4
Affiliations

A photoelectrochemical immunosensor based on Z-scheme CdS composite heterojunction for aflatoxin B1

Fubin Pei et al. Biosens Bioelectron. .

Abstract

Aflatoxin B1 (AFB1) is a highly toxic fungal contaminant widely found in agricultural products. It causes serious harm to human health and the environment. Thus, a fast and sensitive detection approach is urgently needed to prevent AFB1-contaminated products from entering the market effectively. A photoelectrochemical (PEC) immunosensor was developed based on tungsten trioxide/cadmium sulfide core/shell coated with a composite layer consisting of polydopamine and loaded gold nanoparticles (WO3/CdS@PDA/Au) for AFB1 detection. CdS formed a heterojunction with WO3, which improved the photoelectric performance. The coated PDA reducing CdS toxicity was demonstrated by biological experiment of Bacillus subtilis. PDA and Au NPs promoted electron transfer between the semiconductors, being beneficial promoting the photoelectron transfer. Additionally, the antibodies were immobilized on WO3/CdS@PDA/Au via the reactive quinones on the surface of the PDA and electrostatic adsorption from Au NPs. The WO3/CdS@PDA/Au composite as a Z-scheme heterojunction possessed high performance of photocurrent response, and the photoproduced electron/hole transfer path was speculated by electrons spin-resonance spectroscopy technique. Under the optimum experimental conditions, the PEC immunosensor showed a wide linear detection range from 0.05 to 100 ng mL-1 for AFB1, indicating that the immunosensor has a bright application prospect.

Keywords: Aflatoxin B1; Photoelectrochemical immunosensor; WO(3)/CdS@PDA/Au; Z-Scheme heterojunction.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

LinkOut - more resources