Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jul 1;93(3):e2022086.
doi: 10.23750/abm.v93i3.12576.

Research productivity in the genetics of papillary thyroid carcinoma (1991-2020): a bibliometric analysis

Affiliations

Research productivity in the genetics of papillary thyroid carcinoma (1991-2020): a bibliometric analysis

Mohammad Al Hamad et al. Acta Biomed. .

Abstract

Background and aim: Papillary thyroid carcinoma accounts for 85% of thyroid follicular epithelial-derived cancers. The identification of pathogenetic mechanisms improved the understating of papillary thyroid carcinoma pathogenesis. The current study aims to examine the research productivity and trends in the genetics of papillary thyroid carcinoma from 1991 to 2020.

Methods: The Web of Science Core Collection database was searched to retrieve the relevant literature. A search string was applied and 1,741 relevant records were selected for the analysis. Bibliometric techniques were used in the statistical analysis with the help of Biblioshiny (RStudio).

Results: The growth in the number of publications was observed to be over a hundred publications per year since 2015. 'Thyroid' published the highest number of publications, followed by 'Journal of Clinical Endocrinology & Metabolism'. 'Nikiforov YE' was identified as the most productive researcher with a total of 49 publications. Out of the top 20 most contributing researchers, seven belonged to Italy, and four were from the USA. 'University of Pittsburgh' contributed the highest number of publications. The top contributing countries in this field were the USA, China, and Italy. BRAF and RAS were among the frequently used keywords.

Conclusions: This bibliometric review demonstrates that investigating the genetics underlying papillary thyroid carcinoma is a rapidly growing area of research. During the last two decades, China has been a significant contributor to the field. Besides, institutions in USA and Italy have significantly contributed to research in the genetics of papillary thyroid carcinoma. (www.actabiomedica.it).

PubMed Disclaimer

Conflict of interest statement

Each author declares that he/she has no commercial associations (e.g., consultancies, stock ownership, equity interest, patent/licensing arrangement etc.) that might pose a conflict of interest in connection with the submitted article.

Figures

Figure 1:
Figure 1:
Yearly growth and citations of the genetics of papillary thyroid cancer research
Figure 2.
Figure 2.
Authorship pattern of the genetics of papillary thyroid cancer research
Figure 3.
Figure 3.
Top 20 country collaborations in the genetics of papillary thyroid cancer research
Figure 4.
Figure 4.
Most frequently used keywords in the genetics of papillary thyroid cancer research

Similar articles

References

    1. Thyroid Cancer — Cancer Stat Facts (nd) Retrieved August 22, 2021, from https://seercancergov/statfacts/html/thyrohtml.
    1. Pelizzo MR, Boschin IM, Toniato A, et al. Papillary thyroid carcinoma: 35-year outcome and prognostic factors in 1858 patients. Clin Nucl Med. 2007;32:440–4. - PubMed
    1. Fagin JA. How thyroid tumors start and why it matters: kinase mutants as targets for solid cancer pharmacotherapy. J Endocrinol. 2004;183:249–56. - PubMed
    1. Kondo T, Ezzat S, Asa SL. Pathogenetic mechanisms in thyroid follicular-cell neoplasia. Nat Rev Cancer. 2006;6:292–306. - PubMed
    1. Musa HH, Musa IH, El-Shareif M, Musa TH. Global scientific research progress in thyroid cancer: a bibliometric analysis. J Tumour. 2021;9:579–86.