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Review
. 2022 Nov:131:124-133.
doi: 10.1016/j.semcdb.2022.05.008. Epub 2022 May 21.

Tissue hydraulics in reproduction

Affiliations
Review

Tissue hydraulics in reproduction

Chii Jou Chan et al. Semin Cell Dev Biol. 2022 Nov.

Abstract

The development of functional eggs and sperm are critical processes in mammalian development as they ensure successful reproduction and species propagation. While past studies have identified important genes that regulate these processes, the roles of luminal flow and fluid stress in reproductive biology remain less well understood. Here, we discuss recent evidence that support the diverse functions of luminal fluid in oogenesis, spermatogenesis and embryogenesis. We also review emerging techniques that allow for precise quantification and perturbation of tissue hydraulics in female and male reproductive systems, and propose new questions and approaches in this field. We hope this review will provide a useful resource to inspire future research in tissue hydraulics in reproductive biology and diseases.

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Conflict of interest statement

Declaration of Competing Interest The authors declare no competing interests.

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