Antioxidants and Bioactive Compounds in Food: Critical Review of Issues and Prospects

doi:10.3390/antiox11040742

Review

. 2022 Apr 8;11(4):742.

doi: 10.3390/antiox11040742.

Antioxidants and Bioactive Compounds in Food: Critical Review of Issues and Prospects

Mia Kurek¹, Nadjet Benaida-Debbache², Ivona Elez Garofulić¹, Kata Galić¹, Sylvie Avallone^{3

4}, Andrée Voilley^{5

6}, Yves Waché^{5

6}

Affiliations

¹ Department of Food Engineering, Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10000 Zagreb, Croatia.
² Laboratoire de Biochimie Appliquée, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia 06000, Algeria.
³ QualiSud, University of Montpellier, 34000 Montpellier, France.
⁴ CIRAD, Institut Universitaire de Technologie d'Avignon, 84029 Avignon, France.
⁵ International Joint Research Laboratory "Tropical Bioresources & Biotechnology" UMR PAM, Institut Agro Dijon, Université de Bourgogne, 1 Esplanade Erasme, 21078 Dijon, France.
⁶ The School of Biotechnology and Food Technology, Hanoi University of Science and Technology, Hanoi 100000, Vietnam.

PMID: 35453425
PMCID: PMC9029822
DOI: 10.3390/antiox11040742

Review

Antioxidants and Bioactive Compounds in Food: Critical Review of Issues and Prospects

Mia Kurek et al. Antioxidants (Basel). 2022.

. 2022 Apr 8;11(4):742.

doi: 10.3390/antiox11040742.

Authors

Mia Kurek¹, Nadjet Benaida-Debbache², Ivona Elez Garofulić¹, Kata Galić¹, Sylvie Avallone^{3

4}, Andrée Voilley^{5

6}, Yves Waché^{5

6}

Affiliations

¹ Department of Food Engineering, Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10000 Zagreb, Croatia.
² Laboratoire de Biochimie Appliquée, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia 06000, Algeria.
³ QualiSud, University of Montpellier, 34000 Montpellier, France.
⁴ CIRAD, Institut Universitaire de Technologie d'Avignon, 84029 Avignon, France.
⁵ International Joint Research Laboratory "Tropical Bioresources & Biotechnology" UMR PAM, Institut Agro Dijon, Université de Bourgogne, 1 Esplanade Erasme, 21078 Dijon, France.
⁶ The School of Biotechnology and Food Technology, Hanoi University of Science and Technology, Hanoi 100000, Vietnam.

PMID: 35453425
PMCID: PMC9029822
DOI: 10.3390/antiox11040742

Abstract

This review paper gives an insight into the effective delivery mechanisms for health-promoting substances and highlights the challenges of using antioxidants and bioactives in foods. The selection criteria for choosing bioactives and their extraction in bioavailable form with their adequate incorporation techniques and delivery mechanisms are covered. Moreover, an overview of existing methods for determination of bioactivity is given. The importance of scientifically evaluating the effects of foods or food components on consumer health before making claims about the healthiness is aligned. Finally, a scientific perspective on how to respond to the booming demand for health-promoting products is given, and we acknowledge that despite the work done, there are still many challenges that need to be overcome.

Keywords: bioactive compounds; bioavailability; encapsulation; food grade.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

**Figure 1**
From raw material to the meeting of consumers’ needs.

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References

1. Rivera D., Alcaraz F., Verde A., Fajardo J., Valdés A., Obón C., Egea T., Moreno C., Signorini M.A., Palazón J.A., et al. Is there nothing new under the sun? The influence of herbals and pharmacopoeias on ethnobotanical traditions in Albacete (Spain) J. Ethnopharmacol. 2017;4:96–117. doi: 10.1016/j.jep.2016.11.040. - DOI - PubMed
1. Dung H.T., Grushvitski I.V. A new species of the genus Panax (Araliaceae) from Vietnam. Bot. Zhurnal. 1985;70:518–522.
1. Dàn N. Un Tapis de Ginseng sur le Mont Ngoc Linh sur les Hauts Plateaux du Centre. [(accessed on 1 March 2022)]. Available online: https://www.lecourrier.vn/un-tapis-de-ginseng-sur-le-mont-ngoc-linh-sur-....
1. Annonymous. [(accessed on 1 March 2022)]. Available online: https://www.iucnredlist.org/about/background-history.
1. Pham Q.T., Nguyen V.T., Nguyen H.H., Phung D.T., Pham T.D., Trinh N.B., Bui T.T., Nguyen T.S., Nguyen Q.H., Nguyen T.H.A., et al. Possible planting areas for Panax vietnamensis var. fuscidiscus toward poverty reduction in Vietnam. World J. Adv. Res. Rev. 2019;2:22–27. doi: 10.30574/wjarr.2019.2.1.0034. - DOI

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[1] Rivera D., Alcaraz F., Verde A., Fajardo J., Valdés A., Obón C., Egea T., Moreno C., Signorini M.A., Palazón J.A., et al. Is there nothing new under the sun? The influence of herbals and pharmacopoeias on ethnobotanical traditions in Albacete (Spain) J. Ethnopharmacol. 2017;4:96–117. doi: 10.1016/j.jep.2016.11.040. - DOI - PubMed

[2] Rivera D., Alcaraz F., Verde A., Fajardo J., Valdés A., Obón C., Egea T., Moreno C., Signorini M.A., Palazón J.A., et al. Is there nothing new under the sun? The influence of herbals and pharmacopoeias on ethnobotanical traditions in Albacete (Spain) J. Ethnopharmacol. 2017;4:96–117. doi: 10.1016/j.jep.2016.11.040. - DOI - PubMed

[3] Dung H.T., Grushvitski I.V. A new species of the genus Panax (Araliaceae) from Vietnam. Bot. Zhurnal. 1985;70:518–522.

[4] Dung H.T., Grushvitski I.V. A new species of the genus Panax (Araliaceae) from Vietnam. Bot. Zhurnal. 1985;70:518–522.

[5] Dàn N. Un Tapis de Ginseng sur le Mont Ngoc Linh sur les Hauts Plateaux du Centre. [(accessed on 1 March 2022)]. Available online: https://www.lecourrier.vn/un-tapis-de-ginseng-sur-le-mont-ngoc-linh-sur-....

[6] Dàn N. Un Tapis de Ginseng sur le Mont Ngoc Linh sur les Hauts Plateaux du Centre. [(accessed on 1 March 2022)]. Available online: https://www.lecourrier.vn/un-tapis-de-ginseng-sur-le-mont-ngoc-linh-sur-....

[7] Annonymous. [(accessed on 1 March 2022)]. Available online: https://www.iucnredlist.org/about/background-history.

[8] Annonymous. [(accessed on 1 March 2022)]. Available online: https://www.iucnredlist.org/about/background-history.

[9] Pham Q.T., Nguyen V.T., Nguyen H.H., Phung D.T., Pham T.D., Trinh N.B., Bui T.T., Nguyen T.S., Nguyen Q.H., Nguyen T.H.A., et al. Possible planting areas for Panax vietnamensis var. fuscidiscus toward poverty reduction in Vietnam. World J. Adv. Res. Rev. 2019;2:22–27. doi: 10.30574/wjarr.2019.2.1.0034. - DOI

[10] Pham Q.T., Nguyen V.T., Nguyen H.H., Phung D.T., Pham T.D., Trinh N.B., Bui T.T., Nguyen T.S., Nguyen Q.H., Nguyen T.H.A., et al. Possible planting areas for Panax vietnamensis var. fuscidiscus toward poverty reduction in Vietnam. World J. Adv. Res. Rev. 2019;2:22–27. doi: 10.30574/wjarr.2019.2.1.0034. - DOI

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Antioxidants and Bioactive Compounds in Food: Critical Review of Issues and Prospects

Affiliations

Antioxidants and Bioactive Compounds in Food: Critical Review of Issues and Prospects

Authors

Affiliations

Abstract

Conflict of interest statement

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