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Case Reports
. 2022 Jan 24:41:65.
doi: 10.11604/pamj.2022.41.65.29526. eCollection 2022.

Solitary gastric Peutz-Jeghers polyp: a case report

Amal Khsiba  1 , Samir Bradai  1 , Abdelawaheb Nakhli  1 , Emna Chelbi  2 , Moufida Mahmoudi  1 , Asma Ben Mohamed  1 , Mouna Medhioub  1 , Lamine Hamzaoui  1 , Mohamed Mousadek Azouz  1
Affiliations
Case Reports

Solitary gastric Peutz-Jeghers polyp: a case report

Amal Khsiba et al. Pan Afr Med J. .

Abstract

Peutz-Jeghers syndrome is an inherited condition that is characterized by mucocutaneous pigmentation and hamartomatous polyposis in the gastrointestinal tract. It increases significantly the risk for developing of several cancers such as breast, colon, rectum, pancreas and stomach. Solitary Peutz-Jeghers polyp is defined as a unique hamartomatous polyp having the same histological features as Peutz-Jeghers syndrome polyps without associated intestinal polyposis, mucocutaneous pigmentation and family history of Peutz-Jeghers syndrome. Gastric solitary Peutz-Jeghers polyp is extremely rare. We found only 13 cases in the literature. We report a new case of solitary gastric Peutz-Jeghers polyp associated with a branch duct intraductal papillary mucinous neoplasm revealed by an acute pancreatitis. Computed tomography of the abdomen found a branch duct intraductal papillary mucinous neoplasm with a pedicled polypoid formation in the greater gastric curvature. Endoscopic resection was performed without complications. Histologic examination showed Peutz-Jeghers hamartomatous polyp. The risk of cancer remains unclear in this entity. Therefore, the follow-up of these patients is necessary because of the possible risk of malignancy.

Keywords: Peutz-Jeghers syndrome; cancer; case report; pancreatitis; rectum.

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Figures

Figure 1
Figure 1
gastroscopy showed a pedunculated polyp measuring 40 mm in the greater curvature
Figure 2
Figure 2
macroscopic appearance of the polyp after endoscopic resection
Figure 3
Figure 3
(A, B, C, D) histological examination of the polyp showed branching bundles of smooth muscle fibers from the muscularis mucosae extended to the polyp
Figure 4
Figure 4
pancreatic magnetic resonance imaging showed branch duct intraductal papillary mucinous neoplasm of the head of the pancreas
See this image and copyright information in PMC

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