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Case Reports
. 2022 Mar 26;2022(3):rjac097.
doi: 10.1093/jscr/rjac097. eCollection 2022 Mar.

Case report of mesenteric solitary fibrous tumour and review of the literature: 'once in a blue moon'

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Case Reports

Case report of mesenteric solitary fibrous tumour and review of the literature: 'once in a blue moon'

Antonella Nicotera et al. J Surg Case Rep. .

Abstract

Solitary fibrous tumour (SFT) is a rare mesenchymal tumour, usually originating from the serous surfaces, typically of the pleura and pericardium. However, it can also have localizations in soft tissues and visceral organs. We report the case of a 79-year-old woman affected by mesenteric SFT, localized in the sigmoid colon. We performed open excision of the abovementioned mass en-bloc with the sigmoid colon and left adnexal tissues. Pathological examination of surgical specimen revealed a diagnosis of SFT CD34+, high-risk of metastases. Mesenteric SFTs are even rarer forms of SFT and may be asymptomatic or cause intestinal occlusion. There is no consensus on the management of this tumour. Radical surgical excision is the only curative treatment, while adjuvant therapies are indicated in case of advanced disease. Due to the high metastatic risk of malignant forms, a long follow-up is mandatory in these cases.

Keywords: case-report; mesenchymal neoplasm; oncological surgery; rare neoplasm; solitary fibrous tumour.

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Figures

Figure 1
Figure 1
Pre-operative abdominal contrast-enhanced CT scan. Solid mass in the left pelvic quadrant originating from sigmoid mesentery, partially non-dissociable from the left round ligament, is appreciable.
Figure 2
Figure 2
Hematossilin–eosin section showing mild–moderate cytological atypia and minimal necrosis. Courtesy of Dr Ottinetti.
Figure 3
Figure 3
(A and B) The neoplastic cells demonstrate intense diffuse positivity for immunohistochemical staining with CD34 (A), negativity for c-Kit (B). Courtesy of Dr Ottinetti.
Figure 4
Figure 4
Abdominal contrast-enhanced CT scan 4 months after surgery: no evidence of local recurrence.

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References

    1. Goodlad JR, Fletcher CD. Solitary fibrous tumor arising at unusual sites: analysis of a series. Histopathology 1991;19:51222. - PubMed
    1. Gronchi A, Miah AB, Dei Tos AP, Casali PG, Stacchiotti S, on behalf of the ESMO Guidelines Committee, EURACAN and GENTURIS. Soft tissue and visceral sarcomas: ESMO–EURACAN–GENTURIS clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 2021;32:1348–65. - PubMed
    1. Stout AP. Hemangiopericytoma. A study of twenty-five new cases. Cancer 1949;2:1027–54. - PubMed
    1. Fletcher CD, Bridge JA, Pancras CW (eds). World Health Organization Classification of Tumours of Soft Tissue and Bone. Lyon, France: IARC Press, 2013.
    1. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK. WHO Classification of Tumours of the Central Nervous System. World Health Organization Classification of Tumours, 4th edn. Lyon, France: International Agency for Research on Cancer, 2007.

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