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. 2021 Aug 11:35:103.
doi: 10.47176/mjiri.35.103. eCollection 2021.

Predictors of death in patients with COVID-19: A cross-sectional study in West of Iran

Manoochehr Karami  1   2 , Mohammad Mirzaei  3 , Fatemeh Shahbazi  1   4 , Fariba Keramat  5 , Ebrahim Jalili  6 , Saeid Bashirian  7 , Rashid Heidarimoghadam  8 , Jalal Bathaei  3 , Salman Khazaei  9   10
Affiliations

Predictors of death in patients with COVID-19: A cross-sectional study in West of Iran

Manoochehr Karami et al. Med J Islam Repub Iran. .

Abstract

Background: Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a newly identified coronavirus. Our knowledge about the survival rate and prognostic factors of the disease is not established well. The purpose of this study was to evaluate the predictors of COVID-19 mortality in Hamadan province in western Iran. Methods: In this study, we included all laboratory-confirmed COVID-19 cases with known treatment outcomes in Hamadan province, Iran, between 20, 2020, to May 10, 2020. Demographic, clinical, laboratory data, and treatment outcomes were obtained from computerized medical records and compared between survived cases and patients with death outcomes. Univariable and multivariable logistic regression models were used to determine the predictors of death. Results: From 749 investigated patients, 77 patients (10.28%) died during the treatment. The Mean age of patients was 53.97±19.04 years. Multivariable logistic regression showed that males had 2.07 (95% CI: 1.73, 2.54) fold higher odds of death. Those with 60 years old and more had 6.49 (95% CI: 4.53, 7.93) fold higher odds of death. Patients with an underlying disease had 7.14 (95% CI: 6.94, 7.38) fold higher odds of death, and patients who were hospitalized in the ICU ward had 2.24 (95% CI: 1.75, 2.90) times higher odds of COVID-19 related mortality. Conclusion: The potential predictors of death in COVID-19 cases, including the male gender, older age, and having an underlying disease could help physicians to identify patients with poor prognoses at an early stage and better management of them.

Keywords: COVID-19; Coronavirus; Epidemiology; Iran; Mortality.

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