Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Mar;21(3):355-376.
doi: 10.1080/14760584.2022.2021074. Epub 2021 Dec 28.

The race for a COVID-19 vaccine: where are we up to?

Md Kamal Hossain  1 , Majid Hassanzadeganroudsari  1 , Jack Feehan  1   2 , Vasso Apostolopoulos  1
Affiliations
Free article

The race for a COVID-19 vaccine: where are we up to?

Md Kamal Hossain et al. Expert Rev Vaccines. 2022 Mar.
Free article

Abstract

Introduction: A novel strain of coronavirus, SARS-CoV-2, has triggered a global pandemic of coronavirus disease (COVID-19) in late 2019. In January 2020, the WHO declared this pandemic a public health emergency. This pandemic has already caused over 5.3 million deaths from more than 272 million infections. The development of a successful vaccine is an urgent global priority to halt the spread of SARS-CoV-2 and prevent further fatalities. Researchers are fast-tracking this process, and there have already been significant developments in preclinical and clinical phases in a relatively short period of time. Some vaccines have been approved either for emergency use or mass application in recent months.

Areas covered: Herein, we provide a general understanding of the fast-tracked clinical trial procedures and highlight recent successes in preclinical and clinical trials to generate a clearer picture of the progress of COVID-19 vaccine development.

Expert opinion: A good number of vaccines have been rolled out within a short period a feat unprecedented in medical history. However, the emergence of new variants over time has appeared as a new threat, and the number of infections and casualties is still on the rise and this is going to be an ongoing battle.

Keywords: COVID-19; clinical; fast track; pandemic; preclinical; vaccine.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

Substances

LinkOut - more resources