Association of Persistent Pulmonary Hypertension in Infants With the Timing and Type of Antidepressants In Utero

doi:10.1001/jamanetworkopen.2021.36639

. 2021 Dec 1;4(12):e2136639.

doi: 10.1001/jamanetworkopen.2021.36639.

Association of Persistent Pulmonary Hypertension in Infants With the Timing and Type of Antidepressants In Utero

Trine Munk-Olsen¹, Veerle Bergink², Anna-Sophie Rommel², Natalie Momen³, Xiaoqin Liu³

Affiliations

¹ Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
² Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.
³ The National Centre for Register-based Research, Aarhus University, Aarhus Denmark.

PMID: 34851402
PMCID: PMC8637253
DOI: 10.1001/jamanetworkopen.2021.36639

Association of Persistent Pulmonary Hypertension in Infants With the Timing and Type of Antidepressants In Utero

Trine Munk-Olsen et al. JAMA Netw Open. 2021.

. 2021 Dec 1;4(12):e2136639.

doi: 10.1001/jamanetworkopen.2021.36639.

Authors

Trine Munk-Olsen¹, Veerle Bergink², Anna-Sophie Rommel², Natalie Momen³, Xiaoqin Liu³

Affiliations

¹ Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
² Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.
³ The National Centre for Register-based Research, Aarhus University, Aarhus Denmark.

PMID: 34851402
PMCID: PMC8637253
DOI: 10.1001/jamanetworkopen.2021.36639

Abstract

This population-based cohort study examines the risk of persistent pulmonary hypertension among newborns in Denmark after antidepressant exposure in utero.

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Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Cited by

Timing of Antidepressant Discontinuation During Pregnancy and Postpartum Psychiatric Outcomes in Denmark and Norway.
Trinh NTH, Munk-Olsen T, Wray NR, Bergink V, Nordeng HME, Lupattelli A, Liu X. Trinh NTH, et al. JAMA Psychiatry. 2023 May 1;80(5):441-450. doi: 10.1001/jamapsychiatry.2023.0041. JAMA Psychiatry. 2023. PMID: 36884236 Free PMC article.
Consensus Panel Recommendations for the Pharmacological Management of Pregnant Women with Depressive Disorders.
Eleftheriou G, Zandonella Callegher R, Butera R, De Santis M, Cavaliere AF, Vecchio S, Pistelli A, Mangili G, Bondi E, Somaini L, Gallo M, Balestrieri M, Albert U. Eleftheriou G, et al. Int J Environ Res Public Health. 2023 Aug 11;20(16):6565. doi: 10.3390/ijerph20166565. Int J Environ Res Public Health. 2023. PMID: 37623151 Free PMC article.

References

1. Chambers CD, Hernandez-Diaz S, Van Marter LJ, et al. . Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn. N Engl J Med. 2006;354(6):579-587. doi:10.1056/NEJMoa052744 - DOI - PubMed
1. Grigoriadis S, Vonderporten EH, Mamisashvili L, et al. . Prenatal exposure to antidepressants and persistent pulmonary hypertension of the newborn: systematic review and meta-analysis. BMJ. 2014;348:f6932. doi:10.1136/bmj.f6932 - DOI - PMC - PubMed
1. Masarwa R, Bar-Oz B, Gorelik E, Reif S, Perlman A, Matok I. Prenatal exposure to selective serotonin reuptake inhibitors and serotonin norepinephrine reuptake inhibitors and risk for persistent pulmonary hypertension of the newborn: a systematic review, meta-analysis, and network meta-analysis. Am J Obstet Gynecol. 2019;220(1):57.e1-57.e13. doi:10.1016/j.ajog.2018.08.030 - DOI - PubMed
1. Kildemoes HW, Sørensen HT, Hallas J. The Danish National Prescription Registry. Scand J Public Health. 2011;39(7)(suppl):38-41. doi:10.1177/1403494810394717 - DOI - PubMed
1. Schmidt M, Schmidt SA, Sandegaard JL, Ehrenstein V, Pedersen L, Sørensen HT. The Danish National Patient Registry: a review of content, data quality, and research potential. Clin Epidemiol. 2015;7:449-490. doi:10.2147/CLEP.S91125 - DOI - PMC - PubMed

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[1] Chambers CD, Hernandez-Diaz S, Van Marter LJ, et al. . Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn. N Engl J Med. 2006;354(6):579-587. doi:10.1056/NEJMoa052744 - DOI - PubMed

[2] Chambers CD, Hernandez-Diaz S, Van Marter LJ, et al. . Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn. N Engl J Med. 2006;354(6):579-587. doi:10.1056/NEJMoa052744 - DOI - PubMed

[3] Grigoriadis S, Vonderporten EH, Mamisashvili L, et al. . Prenatal exposure to antidepressants and persistent pulmonary hypertension of the newborn: systematic review and meta-analysis. BMJ. 2014;348:f6932. doi:10.1136/bmj.f6932 - DOI - PMC - PubMed

[4] Grigoriadis S, Vonderporten EH, Mamisashvili L, et al. . Prenatal exposure to antidepressants and persistent pulmonary hypertension of the newborn: systematic review and meta-analysis. BMJ. 2014;348:f6932. doi:10.1136/bmj.f6932 - DOI - PMC - PubMed

[5] Masarwa R, Bar-Oz B, Gorelik E, Reif S, Perlman A, Matok I. Prenatal exposure to selective serotonin reuptake inhibitors and serotonin norepinephrine reuptake inhibitors and risk for persistent pulmonary hypertension of the newborn: a systematic review, meta-analysis, and network meta-analysis. Am J Obstet Gynecol. 2019;220(1):57.e1-57.e13. doi:10.1016/j.ajog.2018.08.030 - DOI - PubMed

[6] Masarwa R, Bar-Oz B, Gorelik E, Reif S, Perlman A, Matok I. Prenatal exposure to selective serotonin reuptake inhibitors and serotonin norepinephrine reuptake inhibitors and risk for persistent pulmonary hypertension of the newborn: a systematic review, meta-analysis, and network meta-analysis. Am J Obstet Gynecol. 2019;220(1):57.e1-57.e13. doi:10.1016/j.ajog.2018.08.030 - DOI - PubMed

[7] Kildemoes HW, Sørensen HT, Hallas J. The Danish National Prescription Registry. Scand J Public Health. 2011;39(7)(suppl):38-41. doi:10.1177/1403494810394717 - DOI - PubMed

[8] Kildemoes HW, Sørensen HT, Hallas J. The Danish National Prescription Registry. Scand J Public Health. 2011;39(7)(suppl):38-41. doi:10.1177/1403494810394717 - DOI - PubMed

[9] Schmidt M, Schmidt SA, Sandegaard JL, Ehrenstein V, Pedersen L, Sørensen HT. The Danish National Patient Registry: a review of content, data quality, and research potential. Clin Epidemiol. 2015;7:449-490. doi:10.2147/CLEP.S91125 - DOI - PMC - PubMed

[10] Schmidt M, Schmidt SA, Sandegaard JL, Ehrenstein V, Pedersen L, Sørensen HT. The Danish National Patient Registry: a review of content, data quality, and research potential. Clin Epidemiol. 2015;7:449-490. doi:10.2147/CLEP.S91125 - DOI - PMC - PubMed

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Association of Persistent Pulmonary Hypertension in Infants With the Timing and Type of Antidepressants In Utero

Affiliations

Association of Persistent Pulmonary Hypertension in Infants With the Timing and Type of Antidepressants In Utero

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