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Review
. 2021 Oct 21:2021:2391917.
doi: 10.1155/2021/2391917. eCollection 2021.

Research Progress of PCNA in Reproductive System Diseases

Jing Pan  1 , Jianwei Zhang  2
Affiliations
Review

Research Progress of PCNA in Reproductive System Diseases

Jing Pan et al. Evid Based Complement Alternat Med. .

Abstract

Reproductive system diseases have become a public health problem that endangers human physical and mental health. The causes of reproductive diseases are complex and diverse. From a biological point of view, abnormal cell proliferation may affect important physiological functions of reproductive organs and cause various gynecological or andrological diseases. Proliferating cell nuclear antigen (PCNA) is the most commonly used indicator for detecting cell proliferation activity. The up- or downregulation of its expression is of great significance in reproductive system diseases. This review summarizes the significance of the latest research on PCNA expression in reproductive system diseases.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
PCNA expression regulation of proliferative genes in the occurrence and development of gynecological and andrological diseases.
See this image and copyright information in PMC

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