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Comment
. 2022 Jan;32(1):7-8.
doi: 10.1038/s41422-021-00577-8.

How did a novel X-linked gene become essential for male determination?

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Comment

How did a novel X-linked gene become essential for male determination?

Scott William Roy. Cell Res. 2022 Jan.
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Schematics of sex chromosome evolution in mammals.
Modern mammalian X chromosomes date to the evolution of SRY from SOX3 and initial X/Y differentiation (blue/red), in the shared marsupial/placental ancestor. Subsequently, SDX arose by a retroposition of the autosomal gene MUM1 onto the X chromosome. Additional events included acquisition of additional sequence from an autosome (dark gray) and ongoing X/Y differentiation and Y degradation. Times from timetree.org.

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References

    1. Hawkins JR. Human Mutat. 1993;2:347–350. doi: 10.1002/humu.1380020504. - DOI - PubMed
    1. Burt, A. & Trivers, R. Harvard University Press, Cambridge, MA, (2009).
    1. Bull JJ, Bulmer MG. Heredity. 1981;47:347–365. doi: 10.1038/hdy.1981.97. - DOI - PubMed
    1. Zhan, J., Cui, P., Yu, Z., Qu, W. and Luo, M. Cell Res.10.1038/s41422-021-00539-0 (2021). - PubMed
    1. Kumar S, Stecher G, Suleski M, Hedges SB. Mol. Biol. Evol. 2017;34:1812–1819. doi: 10.1093/molbev/msx116. - DOI - PubMed