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. 2022 Feb;30(2):1231-1241.
doi: 10.1007/s00520-021-06504-2. Epub 2021 Aug 30.

Prevalence, correlates, and impact of sleep disturbance in Chinese meningioma patients

Dandan Zhang #  1   2 , Jing Wang #  3 , Xixi Gu #  1 , Zhifeng Gu  4 , Liren Li  5 , Chen Dong  1   4 , Rui Zhao  6 , Xiaomei Zhang  7
Affiliations

Prevalence, correlates, and impact of sleep disturbance in Chinese meningioma patients

Dandan Zhang et al. Support Care Cancer. 2022 Feb.

Abstract

Purpose: Sleep disturbance is common in meningioma patients and may lead to disease aggravation and decreases health-related quality of life (HRQoL). However, the sleep quality of meningioma patients newly diagnosed and ready for surgery has not been well clarified in China. This study aims to evaluate the prevalence, correlates, and impact of sleep disturbance among Chinese meningioma patients.

Methods: In this cross-sectional study, meningioma patients were recruited from the Affiliated Hospital of Nantong University from January 2020 to November 2020. A series of questionnaires were applied: the 0-10 Numerical Rating Scale (NRS), the Hospital Anxiety and Depression Scale (HADS), the Multidimensional Fatigue Inventory (MFI-20), the Epworth Sleepiness Scale (ESS), the Short-Form 36 (SF-36), the Pittsburgh Sleep Quality Index (PSQI). Independent samples t test, Mann-Whitney U test, chi-square analysis, Pearson/Spearman correlation, and binary logistic regression were used to analyze the data.

Results: One hundred meningioma patients completed the questionnaires. Sleep disturbance affected 43% of the meningioma patients and was linked to many concomitant symptoms, such as headache, fatigue, anxiety, and depression. Binary logistic regression indicated that fatigue and headache were independently associated with sleep disturbance of meningioma patients. Meanwhile, severe sleep disturbance led to lower quality of life.

Conclusions: These findings demonstrated that a considerable number of meningioma patients newly diagnosed and ready for surgery suffered from sleep disturbance, potentially contributing to impair HRQoL. Medical personnel should pay more attention to meningioma patients with sleep disturbance and take effective measures to improve sleep quality, with the ultimate goal to improve their HRQoL.

Keywords: Fatigue; Headache; Meningioma; Quality of life; Sleep quality.

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References

    1. Ostrom QT, Gittleman H, Xu J, Kromer C, Wolinsky Y, Kruchko C, Barnholtz-Sloan JS (2016) CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2009–2013. Neuro Oncol 18(suppl_5):v1–v75. https://doi.org/10.1093/neuonc/now207 - DOI - PubMed - PMC
    1. Whittle IR, Smith C, Navoo P, Collie D (2004) Meningiomas Lancet 363(9420):1535–1543. https://doi.org/10.1016/S0140-6736(04)16153-9 - DOI - PubMed
    1. Englot DJ, Chang EF, Vecht CJ (2016) Epilepsy and brain tumors. Handb Clin Neurol 134:267–285. https://doi.org/10.1016/B978-0-12-802997-8.00016-5 - DOI - PubMed - PMC
    1. Taphoorn MJ, Klein M (2004) Cognitive deficits in adult patients with brain tumours. Lancet Neurol 3(3):159–168. https://doi.org/10.1016/S1474-4422(04)00680-5 - DOI - PubMed
    1. Waagemans ML, van Nieuwenhuizen D, Dijkstra M, Wumkes M, Dirven CM, Leenstra S, Reijneveld JC, Klein M, Stalpers LJ (2011) Long-term impact of cognitive deficits and epilepsy on quality of life in patients with low-grade meningiomas. Neurosurgery 69(1):72–78. https://doi.org/10.1227/NEU.0b013e318212badb (discussion 78–79) - DOI - PubMed

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