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Review
. 2022 Jul;67(7):2771-2791.
doi: 10.1007/s10620-021-07158-0. Epub 2021 Jul 31.

Twelve Months with COVID-19: What Gastroenterologists Need to Know

Giulia Concas  1 , Michele Barone  2 , Ruggiero Francavilla  3 , Fernanda Cristofori  3 , Vanessa Nadia Dargenio  3 , Rossella Giorgio  3 , Costantino Dargenio  3 , Vassilios Fanos  4 , Maria Antonietta Marcialis  4
Affiliations
Review

Twelve Months with COVID-19: What Gastroenterologists Need to Know

Giulia Concas et al. Dig Dis Sci. 2022 Jul.

Abstract

Corona virus disease-19 (COVID-19) is the latest global pandemic. COVID-19 is mainly transmitted through respiratory droplets and, apart from respiratory symptoms, patients often present with gastrointestinal symptoms and liver involvement. Given the high percentage of COVID-19 patients that present with gastrointestinal symptoms (GIS), in this review, we report a practical up-to-date reference for the physician in their clinical practice with patients affected by chronic gastrointestinal (GI) diseases (inflammatory bowel disease, coeliac disease, chronic liver disease) at the time of COVID-19. First, we summarised data on the origin and pathogenetic mechanism of SARS-CoV-2. Then, we performed a literature search up to December 2020 examining clinical manifestations of GI involvement. Next, we illustrated and summarised the most recent guidelines on how to adhere to GI procedures (endoscopy, liver biopsy, faecal transplantation), maintaining social distance and how to deal with immunosuppressive treatment. Finally, we focussed on some special conditions such as faecal-oral transmission and gut microbiota. The rapid accumulation of information relating to this condition makes it particularly essential to revise the literature to take account of the most recent publications for medical consultation and patient care.

Keywords: COVID-19; Coeliac disease; Gastrointestinal symptoms; Inflammatory bowel disease; Liver diseases; SARS-CoV-2.

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Conflict of interest statement

The authors have no conflicts of interest relevant to this article to disclose.

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