Evaluation of a rapid antigen detection test (Panbio™ COVID-19 Ag Rapid Test Device) as a point-of-care diagnostic tool for COVID-19 in a pediatric emergency department

doi:10.1002/jmv.27220

. 2021 Dec;93(12):6803-6807.

doi: 10.1002/jmv.27220. Epub 2021 Jul 27.

Evaluation of a rapid antigen detection test (Panbio™ COVID-19 Ag Rapid Test Device) as a point-of-care diagnostic tool for COVID-19 in a pediatric emergency department

Affiliations

¹ Pediatric Department, Hospital Clínico Universitario, Valencia, Spain.
² Department of Pediatrics, University of Valencia, Valencia, Spain.
³ Microbiology Service, Hospital Clínico Universitario, INCLIVA Research Institute, Valencia, Spain.
⁴ Department of Microbiology, School of Medicine, University of Valencia, Valencia, Spain.

PMID: 34289136
PMCID: PMC8426967
DOI: 10.1002/jmv.27220

Evaluation of a rapid antigen detection test (Panbio™ COVID-19 Ag Rapid Test Device) as a point-of-care diagnostic tool for COVID-19 in a pediatric emergency department

Silvia Carbonell-Sahuquillo et al. J Med Virol. 2021 Dec.

. 2021 Dec;93(12):6803-6807.

doi: 10.1002/jmv.27220. Epub 2021 Jul 27.

Authors

Affiliations

¹ Pediatric Department, Hospital Clínico Universitario, Valencia, Spain.
² Department of Pediatrics, University of Valencia, Valencia, Spain.
³ Microbiology Service, Hospital Clínico Universitario, INCLIVA Research Institute, Valencia, Spain.
⁴ Department of Microbiology, School of Medicine, University of Valencia, Valencia, Spain.

PMID: 34289136
PMCID: PMC8426967
DOI: 10.1002/jmv.27220

Abstract

We evaluated the Panbio™ COVID-19 Ag Rapid Test Device as a point-of-care diagnostic tool for COVID-19 in 357 patients at a pediatric emergency department. Thirty-four patients tested positive by reverse transcription polymerase chain reaction, of which 24 were positive by the antigen assay. The sensitivity and specificity of the assay were 70.5% and 100%, respectively.

Keywords: SARS-CoV-2 RNA viral load; clinical sensitivity; emergency department; field evaluation; pediatric patients; rapid antigen assay.

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Conflict of interest statement

The authors declare that there are no conflict of interests.

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References

1. Overview of testing for SARS‐CoV‐2 (COVID‐19). Updated September 18, 2020. https://www.cdc.gov/coronavirus/2019-ncov/hcp/testing-overview.html
1. SARS‐CoV‐2 diagnostic pipeline. Finddx.org. 2021. https://www.finddx.org/covid-19/pipeline
1. Hayer J, Kasapic D, Zemmrich C. Real‐world clinical performance of commercial SARS‐CoV‐2 rapid antigen tests in suspected COVID‐19: a systematic meta‐analysis of available data as per November 20, 2020. Int J Infect Dis. 2021;108:592‐602. - PMC - PubMed
1. Albert E, Torres I, Bueno F, et al. Field evaluation of a rapid antigen test (Panbio COVID‐19 Ag Rapid Test Device) for COVID‐19 diagnosis in primary healthcare centres. Clin Microbiol Infect. 2020;27(472):e7‐472. - PMC - PubMed
1. Villaverde S, Domínguez‐Rodríguez S, Sabrido G, et al. Diagnostic accuracy of the Panbio SARS‐CoV‐2 antigen rapid test compared with RT‐PCR testing of nasopharyngeal samples in the pediatric population. J Pediatr. 2021;232:287‐289. - PMC - PubMed

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[1] Overview of testing for SARS‐CoV‐2 (COVID‐19). Updated September 18, 2020. https://www.cdc.gov/coronavirus/2019-ncov/hcp/testing-overview.html

[2] Overview of testing for SARS‐CoV‐2 (COVID‐19). Updated September 18, 2020. https://www.cdc.gov/coronavirus/2019-ncov/hcp/testing-overview.html

[3] SARS‐CoV‐2 diagnostic pipeline. Finddx.org. 2021. https://www.finddx.org/covid-19/pipeline

[4] SARS‐CoV‐2 diagnostic pipeline. Finddx.org. 2021. https://www.finddx.org/covid-19/pipeline

[5] Hayer J, Kasapic D, Zemmrich C. Real‐world clinical performance of commercial SARS‐CoV‐2 rapid antigen tests in suspected COVID‐19: a systematic meta‐analysis of available data as per November 20, 2020. Int J Infect Dis. 2021;108:592‐602. - PMC - PubMed

[6] Hayer J, Kasapic D, Zemmrich C. Real‐world clinical performance of commercial SARS‐CoV‐2 rapid antigen tests in suspected COVID‐19: a systematic meta‐analysis of available data as per November 20, 2020. Int J Infect Dis. 2021;108:592‐602. - PMC - PubMed

[7] Albert E, Torres I, Bueno F, et al. Field evaluation of a rapid antigen test (Panbio COVID‐19 Ag Rapid Test Device) for COVID‐19 diagnosis in primary healthcare centres. Clin Microbiol Infect. 2020;27(472):e7‐472. - PMC - PubMed

[8] Albert E, Torres I, Bueno F, et al. Field evaluation of a rapid antigen test (Panbio COVID‐19 Ag Rapid Test Device) for COVID‐19 diagnosis in primary healthcare centres. Clin Microbiol Infect. 2020;27(472):e7‐472. - PMC - PubMed

[9] Villaverde S, Domínguez‐Rodríguez S, Sabrido G, et al. Diagnostic accuracy of the Panbio SARS‐CoV‐2 antigen rapid test compared with RT‐PCR testing of nasopharyngeal samples in the pediatric population. J Pediatr. 2021;232:287‐289. - PMC - PubMed

[10] Villaverde S, Domínguez‐Rodríguez S, Sabrido G, et al. Diagnostic accuracy of the Panbio SARS‐CoV‐2 antigen rapid test compared with RT‐PCR testing of nasopharyngeal samples in the pediatric population. J Pediatr. 2021;232:287‐289. - PMC - PubMed

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Evaluation of a rapid antigen detection test (Panbio™ COVID-19 Ag Rapid Test Device) as a point-of-care diagnostic tool for COVID-19 in a pediatric emergency department

Affiliations

Evaluation of a rapid antigen detection test (Panbio™ COVID-19 Ag Rapid Test Device) as a point-of-care diagnostic tool for COVID-19 in a pediatric emergency department

Authors

Affiliations

Abstract

Conflict of interest statement

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