Breast Cancer Metastasis
- PMID: 33983579
- DOI: 10.1007/978-981-32-9620-6_9
Breast Cancer Metastasis
Abstract
Owing to increased awareness of the importance of mammogram and advances in surgical technology, survival rate of patients with primary breast cancer has dramatically increased. Despite all these advances in breast cancer treatment, there are no currently available treatments for this disease once it metastasizes to distant organs including bones, lungs, brain, and liver. This is mainly attributed to the complexity of metastatic process. Recent advances in technology enabled cancer biologists to dissect each step of the metastatic process, and this led to discovery of major players and molecules in this process. In this section, we will discuss recent discovery and advances in the field of breast cancer metastasis research.
Keywords: Breast cancer metastasis; Immune cells; Metastasis mechanisms; Metastasis model; Pre-metastatic niche.
Similar articles
-
Influence of Extracellular Vesicles on Lung Stromal Cells during Breast Cancer Metastasis.Int J Mol Sci. 2023 Jul 22;24(14):11801. doi: 10.3390/ijms241411801. Int J Mol Sci. 2023. PMID: 37511559 Free PMC article. Review.
-
Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis.Breast Cancer Res. 2015 Jul 25;17(1):98. doi: 10.1186/s13058-015-0607-y. Breast Cancer Res. 2015. PMID: 26208975 Free PMC article.
-
Strategies for the discovery and development of therapies for metastatic breast cancer.Nat Rev Drug Discov. 2012 Jun 1;11(6):479-97. doi: 10.1038/nrd2372. Nat Rev Drug Discov. 2012. PMID: 22653217 Review.
-
Metastatic Breast Cancer, Organotropism and Therapeutics: A Review.Curr Cancer Drug Targets. 2021;21(10):813-828. doi: 10.2174/1568009621666210806094410. Curr Cancer Drug Targets. 2021. PMID: 34365922 Review.
-
Establishment of a novel orthotopic model of breast cancer metastasis to the lung.Oncol Rep. 2015 Jun;33(6):2992-8. doi: 10.3892/or.2015.3927. Epub 2015 Apr 27. Oncol Rep. 2015. PMID: 25963127
Cited by
-
Molecular Pathways of Rosmarinic Acid Anticancer Activity in Triple-Negative Breast Cancer Cells: A Literature Review.Nutrients. 2023 Dec 19;16(1):2. doi: 10.3390/nu16010002. Nutrients. 2023. PMID: 38201832 Free PMC article. Review.
-
Construction of a predictive model for breast cancer metastasis based on lncRNAs.Transl Cancer Res. 2023 Feb 28;12(2):387-397. doi: 10.21037/tcr-23-129. Epub 2023 Feb 27. Transl Cancer Res. 2023. PMID: 36915588 Free PMC article.
-
Navigating the Blood-Brain Barrier: Challenges and Therapeutic Strategies in Breast Cancer Brain Metastases.Int J Mol Sci. 2023 Jul 27;24(15):12034. doi: 10.3390/ijms241512034. Int J Mol Sci. 2023. PMID: 37569410 Free PMC article. Review.
-
Integrated transcriptome analysis identifies APPL1/RPS6KB2/GALK1 as immune-related metastasis factors in breast cancer.Open Med (Wars). 2023 Jun 1;18(1):20230732. doi: 10.1515/med-2023-0732. eCollection 2023. Open Med (Wars). 2023. PMID: 37273920 Free PMC article.
-
Tissue density in the progression of breast cancer: Bedside to bench and back again.Curr Opin Biomed Eng. 2022 Jun;22:100383. doi: 10.1016/j.cobme.2022.100383. Epub 2022 Mar 28. Curr Opin Biomed Eng. 2022. PMID: 35463199 Free PMC article.
References
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical