Advance in the use of gold nanoparticles in the treatment of neurodegenerative diseases: new perspectives

doi:10.4103/1673-5374.313040

Review

. 2021 Dec;16(12):2425-2426.

doi: 10.4103/1673-5374.313040.

Advance in the use of gold nanoparticles in the treatment of neurodegenerative diseases: new perspectives

Gustavo de Bem Silveira¹, Alexandre Pastoris Muller², Ricardo Andrez Machado-de-Ávila¹, Paulo Cesar Lock Silveira¹

Affiliations

¹ Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
² Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Universidade do Extremo Sul Catarinense, Criciúma; Programa de Pós Graduação em Farmacologia, UFSC, Florianópolis, SC, Brazil.

PMID: 33907028
PMCID: PMC8374563
DOI: 10.4103/1673-5374.313040

Review

Advance in the use of gold nanoparticles in the treatment of neurodegenerative diseases: new perspectives

Gustavo de Bem Silveira et al. Neural Regen Res. 2021 Dec.

. 2021 Dec;16(12):2425-2426.

doi: 10.4103/1673-5374.313040.

Authors

Gustavo de Bem Silveira¹, Alexandre Pastoris Muller², Ricardo Andrez Machado-de-Ávila¹, Paulo Cesar Lock Silveira¹

Affiliations

¹ Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
² Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Universidade do Extremo Sul Catarinense, Criciúma; Programa de Pós Graduação em Farmacologia, UFSC, Florianópolis, SC, Brazil.

PMID: 33907028
PMCID: PMC8374563
DOI: 10.4103/1673-5374.313040

No abstract available

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Conflict of interest statement

None

Figures

**Figure 1**
GNPs effects to a target area. Gold nanoparticles (GNPs) charged with pharmacological drugs reaching to a target area increasing drug delivery, decreasing inflammation and oxidative stress, also increasing interaction with amyloid-β (Aβ).

See this image and copyright information in PMC

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References

1. Abdelhalim MA, Jarrar BM. Histological alterations in the liver of rats induced by different gold nanoparticle sizes, doses and exposure duration. J Nanobiotechnology. 2012;10:5. - PMC - PubMed
1. Banerjee T, Mitra S, Singh AK, Sharma RK, Maitra AJIjop. Preparation, characterization and biodistribution of ultrafine chitosan nanoparticles. Int J Pharm. 2002;243:93–105. - PubMed
1. Bilal M, Barani M, Sabir F, Rahdar A, Kyzas GZJN. Nanomaterials for the treatment and diagnosis of Alzheimer's disease: an overview. NanoImpact. 2020;20 doi:101016/jimpact2020100251.
1. Bordoni L, Gabbianelli RJA. Mitochondrial DNA and neurodegeneration: any role for dietary antioxidants. Antioxidants (Basel) 2020;9:764. - PMC - PubMed
1. Cabuzu D, Cirja A, Puiu R, Grumezescu AM. Biomedical applications of gold nanoparticles. Curr Top Med Chem. 2015;15:1605–1613. - PubMed

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[1] Abdelhalim MA, Jarrar BM. Histological alterations in the liver of rats induced by different gold nanoparticle sizes, doses and exposure duration. J Nanobiotechnology. 2012;10:5. - PMC - PubMed

[2] Abdelhalim MA, Jarrar BM. Histological alterations in the liver of rats induced by different gold nanoparticle sizes, doses and exposure duration. J Nanobiotechnology. 2012;10:5. - PMC - PubMed

[3] Banerjee T, Mitra S, Singh AK, Sharma RK, Maitra AJIjop. Preparation, characterization and biodistribution of ultrafine chitosan nanoparticles. Int J Pharm. 2002;243:93–105. - PubMed

[4] Banerjee T, Mitra S, Singh AK, Sharma RK, Maitra AJIjop. Preparation, characterization and biodistribution of ultrafine chitosan nanoparticles. Int J Pharm. 2002;243:93–105. - PubMed

[5] Bilal M, Barani M, Sabir F, Rahdar A, Kyzas GZJN. Nanomaterials for the treatment and diagnosis of Alzheimer's disease: an overview. NanoImpact. 2020;20 doi:101016/jimpact2020100251.

[6] Bilal M, Barani M, Sabir F, Rahdar A, Kyzas GZJN. Nanomaterials for the treatment and diagnosis of Alzheimer's disease: an overview. NanoImpact. 2020;20 doi:101016/jimpact2020100251.

[7] Bordoni L, Gabbianelli RJA. Mitochondrial DNA and neurodegeneration: any role for dietary antioxidants. Antioxidants (Basel) 2020;9:764. - PMC - PubMed

[8] Bordoni L, Gabbianelli RJA. Mitochondrial DNA and neurodegeneration: any role for dietary antioxidants. Antioxidants (Basel) 2020;9:764. - PMC - PubMed

[9] Cabuzu D, Cirja A, Puiu R, Grumezescu AM. Biomedical applications of gold nanoparticles. Curr Top Med Chem. 2015;15:1605–1613. - PubMed

[10] Cabuzu D, Cirja A, Puiu R, Grumezescu AM. Biomedical applications of gold nanoparticles. Curr Top Med Chem. 2015;15:1605–1613. - PubMed

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Advance in the use of gold nanoparticles in the treatment of neurodegenerative diseases: new perspectives

Affiliations

Advance in the use of gold nanoparticles in the treatment of neurodegenerative diseases: new perspectives

Authors

Affiliations

Conflict of interest statement

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