A fundamental division in the Alu family of repeated sequences

doi:10.1073/pnas.85.13.4775

Comparative Study

. 1988 Jul;85(13):4775-8.

doi: 10.1073/pnas.85.13.4775.

A fundamental division in the Alu family of repeated sequences

J Jurka¹, T Smith

Affiliations

PMID: 3387438
PMCID: PMC280518
DOI: 10.1073/pnas.85.13.4775

Comparative Study

A fundamental division in the Alu family of repeated sequences

J Jurka et al. Proc Natl Acad Sci U S A. 1988 Jul.

. 1988 Jul;85(13):4775-8.

doi: 10.1073/pnas.85.13.4775.

Authors

J Jurka¹, T Smith

Affiliation

¹ Bionet, Mountain View, CA 94040.

PMID: 3387438
PMCID: PMC280518
DOI: 10.1073/pnas.85.13.4775

Abstract

The Alu family of repeated sequences from the human genome contains two distinct subfamilies. This division is based on different base preferences in a number of diagnostic sequence positions. One subfamily of the sequences, referred to as the Alu-J subfamily, is very similar to 7SL DNA in these positions. The other subfamily, Alu-S, can be divided further into well-defined branches of sequences. These findings revise the previous picture of the Alu family and expose their complex evolutionary dynamics. They reveal sequence variations of potential importance for the proliferation of Alu repeats and relate them to their structural features. In addition, they open the possibility of using different types of Alu sequences as natural markers for studying genetic rearrangements in the genome.

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References

1. J Mol Biol. 1981 Mar 25;147(1):195-7 - PubMed
1. Proc Natl Acad Sci U S A. 1982 Mar;79(5):1497-500 - PubMed
1. EMBO J. 1984 Oct;3(10):2325-32 - PubMed
1. Nature. 1984 Nov 8-14;312(5990):171-2 - PubMed
1. Nucleic Acids Res. 1985 Sep 11;13(17):6105-24 - PubMed

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[1] J Mol Biol. 1981 Mar 25;147(1):195-7 - PubMed

[2] J Mol Biol. 1981 Mar 25;147(1):195-7 - PubMed

[3] Proc Natl Acad Sci U S A. 1982 Mar;79(5):1497-500 - PubMed

[4] Proc Natl Acad Sci U S A. 1982 Mar;79(5):1497-500 - PubMed

[5] EMBO J. 1984 Oct;3(10):2325-32 - PubMed

[6] EMBO J. 1984 Oct;3(10):2325-32 - PubMed

[7] Nature. 1984 Nov 8-14;312(5990):171-2 - PubMed

[8] Nature. 1984 Nov 8-14;312(5990):171-2 - PubMed

[9] Nucleic Acids Res. 1985 Sep 11;13(17):6105-24 - PubMed

[10] Nucleic Acids Res. 1985 Sep 11;13(17):6105-24 - PubMed

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A fundamental division in the Alu family of repeated sequences

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A fundamental division in the Alu family of repeated sequences

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