Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jan 30;13(1):e13004.
doi: 10.7759/cureus.13004.

Coronavirus Disease-Associated Pulmonary Aspergillosis: A Devastating Complication of COVID-19

Affiliations
Case Reports

Coronavirus Disease-Associated Pulmonary Aspergillosis: A Devastating Complication of COVID-19

Adeel Nasrullah et al. Cureus. .

Abstract

Coronavirus disease-19 (COVID-19) has affected more than ninety-three million people worldwide till January 2021. COVID-19 can cause a destructive dysregulated immune response which can result in numerous complications such as kidney failure, myocarditis, and strokes. A new entity called coronavirus disease-associated pulmonary aspergillosis (CAPA) has emerged in recent times. The literature on CAPA is limited. We present a case of CAPA in an immunocompetent patient who was placed on veno-venous extra-corporeal membranous oxygen (VV-ECMO). We briefly explained pathophysiology, clinical presentations, and management of CAPA in this report.

Keywords: corona virus disease 2019 (covid-19); immuno-competent; invasive aspergillosis; vv-ecmo.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Posterior-anterior view of chest X-ray (CXR) at admission (A) and at the diagnosis of invasive aspergillosis (B)
CXR on the left (A) shows bilateral patchy infiltrates as marked by white arrows, while CXR on the right (B) shows dense multilobar patchy consolidations marked by white arrows.
Figure 2
Figure 2. CT chest shows multilobar diffuse consolidations as marked by black arrows

Similar articles

Cited by

References

    1. Aspergillosis complicating severe coronavirus disease. Marr K, Platt A, Tornheim J, Zhang S, Datta K, Cardozo C, Garcia-Vidal C. Emerg Infect Dis. 2021;27:18–25. - PMC - PubMed
    1. Invasive aspergillosis in patients with severe COVID-19 pneumonia. Helleberg M, Steensen M, Arendrup MC. Clin Microbiol Infect. 2021;27:147–148. - PMC - PubMed
    1. COVID-19 associated invasive pulmonary aspergillosis: diagnostic and therapeutic challenges. Mohamed A, Rogers TR, Talento AF. J Fungi. 2020;6:115. - PMC - PubMed
    1. Invasive pulmonary aspergillosis complicating COVID-19 in the ICU - a case report. Prattes J, Valentin T, Hoenigl M, Talakic E, Reisinger AC, Eller P. Medical Mycol Case Rep. 2020 - PMC - PubMed
    1. Invasive aspergillosis as an under-recognized superinfection in COVID-19. Thompson GR III, Cornely OA, Pappas PG, Patterson TF, Hoenigl M, Jenks JD, Clancy CJ. Open Forum Infect Dis. 2020;7:0. - PMC - PubMed

Publication types

LinkOut - more resources