Update Alert 7: Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults

doi:10.7326/L20-1446

. 2021 Feb;174(2):W25-W29.

doi: 10.7326/L20-1446. Epub 2021 Jan 5.

Update Alert 7: Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults

Katherine Mackey¹, Devan Kansagara¹, Kathryn Vela¹

Affiliations

PMID: 33395346
PMCID: PMC7791405
DOI: 10.7326/L20-1446

Update Alert 7: Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults

Katherine Mackey et al. Ann Intern Med. 2021 Feb.

. 2021 Feb;174(2):W25-W29.

doi: 10.7326/L20-1446. Epub 2021 Jan 5.

Authors

Katherine Mackey¹, Devan Kansagara¹, Kathryn Vela¹

Affiliation

¹ VA Portland Health Care System, Portland, Oregon.

PMID: 33395346
PMCID: PMC7791405
DOI: 10.7326/L20-1446

No abstract available

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Conflict of interest statement

Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L20-1446.

Update of

Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults: A Living Systematic Review.
Mackey K, King VJ, Gurley S, Kiefer M, Liederbauer E, Vela K, Sonnen P, Kansagara D. Mackey K, et al. Ann Intern Med. 2020 Aug 4;173(3):195-203. doi: 10.7326/M20-1515. Epub 2020 May 15. Ann Intern Med. 2020. Update in: Ann Intern Med. 2021 Feb;174(2):W25-W29. doi: 10.7326/L20-1446. Update in: Ann Intern Med. 2021 Jun;174(6):W54-W55. doi: 10.7326/L21-0223. PMID: 32422062 Free PMC article. Updated.

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References

1. Mackey K , King VJ , Gurley S , et al. Risks and impact of angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers on SARS-CoV-2 infection in adults. A living systematic review. Ann Intern Med. 2020;173:195-203. doi:10.7326/M20-1515 - DOI - PMC - PubMed
1. Cheng X , Cai G , Wen X , et al. Clinical characteristics and fatal outcomes of hypertension in patients with severe COVID-19. Aging (Albany NY). 2020;12. [PMID: ] doi:10.18632/aging.104019 - DOI - PMC - PubMed
1. COVID-19 RISk and Treatments (CORIST) Collaboration.. RAAS inhibitors are not associated with mortality in COVID-19 patients: findings from an observational multicenter study in Italy and a meta-analysis of 19 studies. Vascul Pharmacol. 2020;135:106805. [PMID: ] doi:10.1016/j.vph.2020.106805 - DOI - PMC - PubMed
1. Genet B , Vidal JS , Cohen A , et al. COVID-19 in-hospital mortality and use of renin-angiotensin system blockers in geriatrics patients. J Am Med Dir Assoc. 2020;21:1539-1545. [PMID: ] doi:10.1016/j.jamda.2020.09.004 - DOI - PMC - PubMed
1. Kalra A , Hawkins ES , Nowacki AS , et al. Angiotensin-converting enzyme inhibitors versus angiotensin II receptor blockers: a comparison of outcomes in patients with COVID-19 [Letter]. Circ Cardiovasc Qual Outcomes. 2020;13:e007115. [PMID: ] doi:10.1161/CIRCOUTCOMES.120.007115 - DOI - PMC - PubMed

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[1] Mackey K , King VJ , Gurley S , et al. Risks and impact of angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers on SARS-CoV-2 infection in adults. A living systematic review. Ann Intern Med. 2020;173:195-203. doi:10.7326/M20-1515 - DOI - PMC - PubMed

[2] Mackey K , King VJ , Gurley S , et al. Risks and impact of angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers on SARS-CoV-2 infection in adults. A living systematic review. Ann Intern Med. 2020;173:195-203. doi:10.7326/M20-1515 - DOI - PMC - PubMed

[3] Cheng X , Cai G , Wen X , et al. Clinical characteristics and fatal outcomes of hypertension in patients with severe COVID-19. Aging (Albany NY). 2020;12. [PMID: ] doi:10.18632/aging.104019 - DOI - PMC - PubMed

[4] Cheng X , Cai G , Wen X , et al. Clinical characteristics and fatal outcomes of hypertension in patients with severe COVID-19. Aging (Albany NY). 2020;12. [PMID: ] doi:10.18632/aging.104019 - DOI - PMC - PubMed

[5] COVID-19 RISk and Treatments (CORIST) Collaboration.. RAAS inhibitors are not associated with mortality in COVID-19 patients: findings from an observational multicenter study in Italy and a meta-analysis of 19 studies. Vascul Pharmacol. 2020;135:106805. [PMID: ] doi:10.1016/j.vph.2020.106805 - DOI - PMC - PubMed

[6] COVID-19 RISk and Treatments (CORIST) Collaboration.. RAAS inhibitors are not associated with mortality in COVID-19 patients: findings from an observational multicenter study in Italy and a meta-analysis of 19 studies. Vascul Pharmacol. 2020;135:106805. [PMID: ] doi:10.1016/j.vph.2020.106805 - DOI - PMC - PubMed

[7] Genet B , Vidal JS , Cohen A , et al. COVID-19 in-hospital mortality and use of renin-angiotensin system blockers in geriatrics patients. J Am Med Dir Assoc. 2020;21:1539-1545. [PMID: ] doi:10.1016/j.jamda.2020.09.004 - DOI - PMC - PubMed

[8] Genet B , Vidal JS , Cohen A , et al. COVID-19 in-hospital mortality and use of renin-angiotensin system blockers in geriatrics patients. J Am Med Dir Assoc. 2020;21:1539-1545. [PMID: ] doi:10.1016/j.jamda.2020.09.004 - DOI - PMC - PubMed

[9] Kalra A , Hawkins ES , Nowacki AS , et al. Angiotensin-converting enzyme inhibitors versus angiotensin II receptor blockers: a comparison of outcomes in patients with COVID-19 [Letter]. Circ Cardiovasc Qual Outcomes. 2020;13:e007115. [PMID: ] doi:10.1161/CIRCOUTCOMES.120.007115 - DOI - PMC - PubMed

[10] Kalra A , Hawkins ES , Nowacki AS , et al. Angiotensin-converting enzyme inhibitors versus angiotensin II receptor blockers: a comparison of outcomes in patients with COVID-19 [Letter]. Circ Cardiovasc Qual Outcomes. 2020;13:e007115. [PMID: ] doi:10.1161/CIRCOUTCOMES.120.007115 - DOI - PMC - PubMed

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Update Alert 7: Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults

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Update Alert 7: Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults

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