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Review
. 2021 Feb;22(2):62-71.
doi: 10.1111/1751-2980.12966.

Novel biomarkers for the diagnosis and prognosis of gallbladder cancer

Hong Ze Lin  1 , Tao Zhang  1 , Ming Yu Chen  2 , Ji Liang Shen  2
Affiliations
Review

Novel biomarkers for the diagnosis and prognosis of gallbladder cancer

Hong Ze Lin et al. J Dig Dis. 2021 Feb.

Abstract

Gallbladder cancer (GBC) is the most common form of biliary tract malignancy with a dismal prognosis. A poor outcome in patients with GBC is related to the aggressive nature of the tumor, delayed diagnosis, and a lack of reliable biomarkers and effective treatment. Therefore, early diagnosis and accurate disease assessment are crucial to prolonging the patient survival. Identification of novel prognostic and diagnostic biomarkers may help improve the early diagnostic rate and develop specific targeted treatments for patients with GBC. We herein review the novel biomarkers that may be associated with the diagnosis and prognosis in GBC and their potential clinical significance in the management of GBC.

Keywords: diagnosis; gallbladder neoplasms; novel biomarker; prognosis.

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