Comment
doi: 10.1016/j.cels.2020.10.008.
The Most Logical Approach to Improve CAR T Cell Therapy
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- PMID: 33212015
- DOI: 10.1016/j.cels.2020.10.008
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Comment
The Most Logical Approach to Improve CAR T Cell Therapy
Cell Syst.
.
Free article
Abstract
Combinational antigen recognition is the most logical way to improve the safety of cancer therapy. CAR T cells therapy, combined with synthetic biology, protein engineering, and bioinformatics, can perform advanced computations to enhance tumor targeting specificity.
Copyright © 2020 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of Interests Patent applications have been filed on CAR designs (S.L, and W.W.W.). W.W.W. is a scientific co-founder, scientific advisory board member and shareholder of Senti Biosciences, and has received research support from Senti Biosciences.
Comment on
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Discriminatory Power of Combinatorial Antigen Recognition in Cancer T Cell Therapies.Cell Syst. 2020 Sep 23;11(3):215-228.e5. doi: 10.1016/j.cels.2020.08.002. Epub 2020 Sep 10. Cell Syst. 2020. PMID: 32916097 Free PMC article.
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