Neural-specific carbohydrate moiety shared by many surface glycoproteins in Drosophila and grasshopper embryos
- PMID: 3320283
- PMCID: PMC6569091
- DOI: 10.1523/JNEUROSCI.07-12-04137.1987
Neural-specific carbohydrate moiety shared by many surface glycoproteins in Drosophila and grasshopper embryos
Abstract
Antiserum against horseradish peroxidase (anti-HRP Ab) labels the surfaces of neurons in both Drosophila and grasshopper (Jan and Jan, 1982). Here we show that the anti-HRP Ab (1) immunoprecipitates at least 17 different membrane glycoproteins from the Drosophila embryo CNS (and a similar array from grasshopper), and (2) recognizes a neural-specific carbohydrate moiety expressed by most if not all of these proteins. Although the anti-HRP Ab stains all axon pathways, 2 of the anti-HRP glycoproteins, fasciclin I and II, are expressed on specific subsets of axon pathways in the grasshopper embryo.
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