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Review
. 2020 Dec;49(4):759-770.
doi: 10.1016/j.ecl.2020.08.004. Epub 2020 Oct 14.

Phthalate Exposure, Adolescent Health, and the Need for Primary Prevention

Clara G Sears  1 , Joseph M Braun  2
Affiliations
Review

Phthalate Exposure, Adolescent Health, and the Need for Primary Prevention

Clara G Sears et al. Endocrinol Metab Clin North Am. 2020 Dec.

Abstract

Phthalates, a class of endocrine-disrupting chemicals, are used widely in many consumer products, and exposure can interfere with a range of hormonal functions during early life. These disruptions may alter development during late childhood and adolescence. This article discusses the potential effects of phthalate exposure on adiposity, puberty, and neurodevelopment during late childhood and adolescence. It also highlights studies of behavioral interventions to reduce phthalate exposures and the roles of health care professionals and policy makers in preventing phthalate exposure.

Keywords: Adolescent health; Endocrine-disrupting chemicals; Neurodevelopment; Obesity; Phthalates; Puberty.

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Conflict of interest statement

Disclosure Dr J.M. Braun was financially compensated for serving as an expert witness for plaintiffs in litigation related to tobacco smoke exposures and received an honorarium for serving on an advisory board to Quest Diagnostics. Dr J.M. Braun served as an expert witness in litigation related to perfluorooctanoic acid contamination in drinking water in New Hampshire. Funds received from this arrangement are paid to Brown University and are not used for direct personal benefit (e.g., salary/fringe, travel).

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