Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jan-Jun;11(1):57-63.
doi: 10.4103/njms.NJMS_70_19. Epub 2020 Jun 18.

Comparative evaluation of buccal pad of fat with and without bovine collagen membrane in the management of oral submucous fibrosis: A prospective clinical study

Arun Pandey  1 , Naresh Kumar Sharma  1 , Neeraj Kumar Dhiman  1 , Chandresh Jaiswara  1 , Preeti Tiwari  1 , Akhilesh Kumar Singh  1 , Vishal Verma  1 , Shankar Singh  1
Affiliations

Comparative evaluation of buccal pad of fat with and without bovine collagen membrane in the management of oral submucous fibrosis: A prospective clinical study

Arun Pandey et al. Natl J Maxillofac Surg. 2020 Jan-Jun.

Abstract

Background: Oral submucous fibrosis (OSMF) is a chronic, debilitating disease characterized by juxtaepithelial fibrosis. The present study evaluates the efficacy of buccal fat pad (BFP) and bovine collagen membrane as reconstruction options.

Materials and methods: The sample size includes 22 patients between 20 and 60 years, randomly distributed in two groups: Group I in which BFP was used and Group II where BFP with bovine collagen membrane was used after surgical resection of fibrotic bands. The clinical evaluation on postoperative 1st, 3rd, and 5th days and 1st, 2nd, 3rd, 4th, 12th, and 24th weeks subsequently.

Results: The mean age in Group I was 27.17 ± 3.157 years and Group II was 37.90 ± 6.657 years. The mean preoperative mouth opening was 9.75 ± 6.717 and 8.90 ± 3.784 mm in Groups I and II, respectively. The mean duration of presenting illness in Group I was 9.75 ± 2.598 years and in Group II was 8.80 ± 1.989 years. There was no significant difference observed between Groups I and II in relation to reduced mouth opening and duration of symptoms (P > 0.05) except for age. No significant difference was observed between both the groups in relation to preoperative pain, burning sensation, cheek stiffness, mucosal suppleness, postoperative infection, and postoperative pain at days 1 and 5 and 1st week. There was a significant difference observed in postoperative pain among both the groups on the 3rd day and 2nd week.

Conclusion: In the present study, both the groups have proved to give better results, as BFP in the form of interposition material showed rapid epithelization and minimum wound contracture.

Keywords: Bovine collagen membrane; buccal pad of fat; mouth opening; oral submucous fibrosis.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Photograph showing defect interpositioned with buccal fat pad graft alone
Figure 2
Figure 2
Photograph showing defect interpositioned with buccal fat pad graft covered with bovine collagen
Graph 1
Graph 1
Graphical representation showing comparison of median Visual Analog Scale score between two groups at different time interval
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Rajalalitha P, Vali S. Molecular pathogenesis of oral submucous fibrosis – A collagen metabolic disorder. J Oral Pathol Med. 2005;34:321–8. - PubMed
    1. Pindborg JJ, Sirsat SM. Oral submucous fibrosis. Oral Surg Oral Med Oral Pathol. 1966;22:764–79. - PubMed
    1. Pindborg JJ, Zheng KH, Kong CR, Lin F ×. Pilot survey of oral mucosa in areca (betel) nut chewers on Hainan Island of the People's Republic of China. Community Dent Oral Epidemiol. 1984;12:195–6. - PubMed
    1. Kramer IR, Pindborg JJ, Bezroukov V, Infirri JS. Guide to epidemiology and diagnosis of oral mucosal diseases and conditions. World Health Organization. Community Dent Oral Epidemiol. 1980;8:1–26. - PubMed
    1. Joshi SG. Submucous fibrosis of the palate and pillars. Indian J Otolaryngol. 1953;4:l–4.