Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Sep 28:8:tkaa035.
doi: 10.1093/burnst/tkaa035. eCollection 2020.

Clinical guideline on topical growth factors for skin wounds

Affiliations

Clinical guideline on topical growth factors for skin wounds

Chun-Mao Han et al. Burns Trauma. .

Abstract

An increased number of patients with skin wounds have been witnessed in the past decades. Among the various kinds of treatments for skin wounds, topical exogenous growth factors are indispensable and have been used in many countries. However, whether they have reliable effects remains controversial, and their application for skin wound treatment needs to be further standardized and optimized in terms of socio-economic considerations. Thus, the Chinese Burn Association developed this guideline indicating efficacy, application details, adverse reactions and precautions of five clinically common topical growth factors using the Grading of Recommendations Assessment Development and Evaluation method to promote the rational application of topical exogenous growth factors in skin wounds and to benefit more patients.

Keywords: GRADE method; Growth factor; Guideline; Skin wound; Wound healing.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Diagram of the development of clinical guideline on topical growth factors for skin wounds using the Grading of Recommendations Assessment Development and Evaluation method

Similar articles

Cited by

References

    1. Sun X, Xie T. Research and related therapies of growth factors in wound healing (Chinese) [J]. J Trauma Surg. 2016; 18: 190–3.
    1. Chen Y, Yao L, Norris S, Du L, Chen H, Zeng X, et al. . Application of GRADE in systematic reviews: necessity, frequently asked questions and concerns (Chinese)[J]. Chin J Evid-based Med. 2013; 13: 1401–4.
    1. Zeng X, Leng W, Li S, Guo Y, Wang P. How to understand and use GRADE system correctly? A briefly outline (Chinese) [J]. Chin J Evid-based Med. 2011; 11: 985–90.
    1. Wang S, Cui X, Fu X, Zhou L, Ma J, Yan S. Recombinant human basic fibroblast growth factor in treating burns and other skin injuries (Chinese) [J]. Chin J Traumatol. 1999; 15: 196–9.
    1. Zhang C, Hong S, Gu C, Huang Z, Du S. Clinical observation of recombinant bovine basic fibroblast growth factor in treating second degree burn wounds (Chinese) [J]. Chin J Burns. 2001; 17: 246–6.