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Review
. 2021 Aug;68(4):695-699.
doi: 10.1002/bab.2033. Epub 2020 Oct 19.

Future developments in biosensors for field-ready SARS-CoV-2 virus diagnostics

Mona Fani  1 , Milad Zandi  2 , Saber Soltani  2 , Samaneh Abbasi  3
Affiliations
Review

Future developments in biosensors for field-ready SARS-CoV-2 virus diagnostics

Mona Fani et al. Biotechnol Appl Biochem. 2021 Aug.

Abstract

According to the evidence, the coronavirus disease 19 (COVID-19) is caused by a zoonotic pathogen named respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus can spread through personal contact, respiratory droplets, and also through airborne transmission. A rapid, low-cost, and effective biosensor platform is essential to diagnose patients with COVID-19 infection, predominantly the asymptomatic individuals, and prevent the spread of the SARS-CoV-2 via transmission routes. The objective of this review is to provide a comparative view among current diagnostic methods, focusing on recently suggested biosensors for the detection of SARS-CoV2 in clinical samples. A capable SARS-CoV-2 biosensor can be designed by the holistic insights of various biosensor studies.

Keywords: COVID-19; SARS-CoV-2; biosensor; coronavirus; real-time PCR; serological assays.

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Figures

FIG. 1
FIG. 1
Schematic illustration of the DNA biosensor.
See this image and copyright information in PMC

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