Primary Gastric Adenosquamous Carcinoma: A Case Report

doi:10.14740/gr1307

Case Reports

. 2020 Aug;13(4):155-157.

doi: 10.14740/gr1307. Epub 2020 Aug 14.

Primary Gastric Adenosquamous Carcinoma: A Case Report

Ragia Aly¹, Sachin Gupta², Sorab Gupta³, Navroop Nagra⁴, Abhinav Goyal⁵, Balraj Singh⁶

Affiliations

¹ Danbury Hospital, 24 Hospital Ave, Danbury, CT 06810, USA.
² Tower Health Reading Hospital, POBox16052, Reading, PA 19612-6052, USA.
³ Hematology Oncology, Einstein Healthcare Network, 5501 Old York, Philadelphia, PA 19141, USA.
⁴ Hepatology, Virgina Mason Medical Center, Seattle, WA, USA.
⁵ Gastroenterology, Einstein Healthcare Network, 5501 Old York, Philadelphia, PA 19141, USA.
⁶ Hematology Oncology, St. Joseph's University Medical Center, 703 Main St, Paterson, NJ 07503, USA.

PMID: 32864027
PMCID: PMC7433371
DOI: 10.14740/gr1307

Case Reports

Primary Gastric Adenosquamous Carcinoma: A Case Report

Ragia Aly et al. Gastroenterology Res. 2020 Aug.

. 2020 Aug;13(4):155-157.

doi: 10.14740/gr1307. Epub 2020 Aug 14.

Authors

Ragia Aly¹, Sachin Gupta², Sorab Gupta³, Navroop Nagra⁴, Abhinav Goyal⁵, Balraj Singh⁶

Affiliations

¹ Danbury Hospital, 24 Hospital Ave, Danbury, CT 06810, USA.
² Tower Health Reading Hospital, POBox16052, Reading, PA 19612-6052, USA.
³ Hematology Oncology, Einstein Healthcare Network, 5501 Old York, Philadelphia, PA 19141, USA.
⁴ Hepatology, Virgina Mason Medical Center, Seattle, WA, USA.
⁵ Gastroenterology, Einstein Healthcare Network, 5501 Old York, Philadelphia, PA 19141, USA.
⁶ Hematology Oncology, St. Joseph's University Medical Center, 703 Main St, Paterson, NJ 07503, USA.

PMID: 32864027
PMCID: PMC7433371
DOI: 10.14740/gr1307

Abstract

Gastric adenosquamous carcinoma (GASC) is a rare variant of gastric cancer; the limited data available suggest that these tumors are more aggressive and have a worse outcome in comparison to gastric adenocarcinoma. Currently, the management of GASC is similar to adenocarcinoma. We report a case of GASC that progressed rapidly despite treatment.

Keywords: Adenocarcinoma; Adenosquamous carcinoma; Gastric cancer; Pembrolizumab; Stomach; Stomach cancer.

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Conflict of interest statement

None to declare.

References

1. American cancer society, Cancer facts and figures 2020. - PMC - PubMed
1. Karimi P, Islami F, Anandasabapathy S, Freedman ND, Kamangar F. Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention. Cancer Epidemiol Biomarkers Prev. 2014;23(5):700–713. doi: 10.1158/1055-9965.EPI-13-1057. - DOI - PMC - PubMed
1. Chen H, Shen C, Yin R, Yin Y, Chen J, Han L, Zhang B. et al. Clinicopathological characteristics, diagnosis, treatment, and outcomes of primary gastric adenosquamous carcinoma. World J Surg Oncol. 2015;13:136. doi: 10.1186/s12957-015-0554-1. - DOI - PMC - PubMed
1. Feng F, Zheng G, Qi J, Xu G, Wang F, Wang Q, Guo M. et al. Clinicopathological features and prognosis of gastric adenosquamous carcinoma. Sci Rep. 2017;7(1):4597. doi: 10.1038/s41598-017-04563-2. - DOI - PMC - PubMed
1. NCCN Guidelines Version 2.2020 Gastric Cancer. https://www.nccn.org/professionals/physician_gls/pdf/gastric.pdf.

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[1] American cancer society, Cancer facts and figures 2020. - PMC - PubMed

[2] American cancer society, Cancer facts and figures 2020. - PMC - PubMed

[3] Karimi P, Islami F, Anandasabapathy S, Freedman ND, Kamangar F. Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention. Cancer Epidemiol Biomarkers Prev. 2014;23(5):700–713. doi: 10.1158/1055-9965.EPI-13-1057. - DOI - PMC - PubMed

[4] Karimi P, Islami F, Anandasabapathy S, Freedman ND, Kamangar F. Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention. Cancer Epidemiol Biomarkers Prev. 2014;23(5):700–713. doi: 10.1158/1055-9965.EPI-13-1057. - DOI - PMC - PubMed

[5] Chen H, Shen C, Yin R, Yin Y, Chen J, Han L, Zhang B. et al. Clinicopathological characteristics, diagnosis, treatment, and outcomes of primary gastric adenosquamous carcinoma. World J Surg Oncol. 2015;13:136. doi: 10.1186/s12957-015-0554-1. - DOI - PMC - PubMed

[6] Chen H, Shen C, Yin R, Yin Y, Chen J, Han L, Zhang B. et al. Clinicopathological characteristics, diagnosis, treatment, and outcomes of primary gastric adenosquamous carcinoma. World J Surg Oncol. 2015;13:136. doi: 10.1186/s12957-015-0554-1. - DOI - PMC - PubMed

[7] Feng F, Zheng G, Qi J, Xu G, Wang F, Wang Q, Guo M. et al. Clinicopathological features and prognosis of gastric adenosquamous carcinoma. Sci Rep. 2017;7(1):4597. doi: 10.1038/s41598-017-04563-2. - DOI - PMC - PubMed

[8] Feng F, Zheng G, Qi J, Xu G, Wang F, Wang Q, Guo M. et al. Clinicopathological features and prognosis of gastric adenosquamous carcinoma. Sci Rep. 2017;7(1):4597. doi: 10.1038/s41598-017-04563-2. - DOI - PMC - PubMed

[9] NCCN Guidelines Version 2.2020 Gastric Cancer. https://www.nccn.org/professionals/physician_gls/pdf/gastric.pdf.

[10] NCCN Guidelines Version 2.2020 Gastric Cancer. https://www.nccn.org/professionals/physician_gls/pdf/gastric.pdf.

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Primary Gastric Adenosquamous Carcinoma: A Case Report

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Primary Gastric Adenosquamous Carcinoma: A Case Report

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