COVID-19 and Central Nervous System: Entry Routes And

doi:10.32598/bcn.11.covid19.2360.1

Review

. 2020 Mar-Apr;11(2):217-224.

doi: 10.32598/bcn.11.covid19.2360.1. Epub 2020 Jul 8.

COVID-19 and Central Nervous System: Entry Routes And

Nooshin Ahmadirad¹, Zahra Ghasemi²

Affiliations

¹ Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
² Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.

PMID: 32855781
PMCID: PMC7368099
DOI: 10.32598/bcn.11.covid19.2360.1

Review

COVID-19 and Central Nervous System: Entry Routes And

Nooshin Ahmadirad et al. Basic Clin Neurosci. 2020 Mar-Apr.

. 2020 Mar-Apr;11(2):217-224.

doi: 10.32598/bcn.11.covid19.2360.1. Epub 2020 Jul 8.

Authors

Nooshin Ahmadirad¹, Zahra Ghasemi²

Affiliations

¹ Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
² Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.

PMID: 32855781
PMCID: PMC7368099
DOI: 10.32598/bcn.11.covid19.2360.1

Abstract

Awareness of the current outbreak of Coronavirus Disease - 2019 (COVID-19) affecting the nervous system and identifying its possible ways to enter the Central Nervous System (CNS) are critical for the prevention and treatment of the disease. Hence, the CNS implications of the COVID-19 since the spread of the virus were reviewed in this study.

Keywords: ACE; COVID-19; Hypoxia; Neural pathway.

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Conflict of interest statement

Conflict of interest The authors declare no conflict of interest and declare that this work was accompanied with no commercial or financial relationships that could be construed as a potential conflict of interest.

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References

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[1] Abdennour L., Zeghal C., Dème M., Puybasset L. (2012). Interaction cerveau-poumon. In Annales Francaises D’anesthesie Et De Reanimation, 31(6), e101–7. [DOI:10.1016/j.annfar.2012.04.013] [PMID ] - DOI - PubMed

[2] Abdennour L., Zeghal C., Dème M., Puybasset L. (2012). Interaction cerveau-poumon. In Annales Francaises D’anesthesie Et De Reanimation, 31(6), e101–7. [DOI:10.1016/j.annfar.2012.04.013] [PMID ] - DOI - PubMed

[3] Baig A. Mannan, Khaleeq A., Ali U., Syeda H. (2020). Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neuro-tropic mechanisms. In ACS Chemical Neuroscience, 11(7):995–8. [DOI:10.1021/acschemneuro.0c00122] [PMID ] [PMCID ] - DOI - PubMed

[4] Baig A. Mannan, Khaleeq A., Ali U., Syeda H. (2020). Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neuro-tropic mechanisms. In ACS Chemical Neuroscience, 11(7):995–8. [DOI:10.1021/acschemneuro.0c00122] [PMID ] [PMCID ] - DOI - PubMed

[5] Bohmwald K., Galvez N., Ríos M., Kalergis A. M. (2018). Neurologic alterations due to respiratory virus infections. Frontiers in Cellular Neuroscience, 12, 386. [DOI:10.3389/fncel.2018.00386] [PMID ] [PMCID ] - DOI - PMC - PubMed

[6] Bohmwald K., Galvez N., Ríos M., Kalergis A. M. (2018). Neurologic alterations due to respiratory virus infections. Frontiers in Cellular Neuroscience, 12, 386. [DOI:10.3389/fncel.2018.00386] [PMID ] [PMCID ] - DOI - PMC - PubMed

[7] Ceccarelli M., Berretta M., Venanzi Rullo E., Nunnari G., Cacopardo B. (2020). Differences and similarities between Severe Acute Respiratory Syndrome (SARS)-CoronaVirus (CoV) and SARS-CoV-2. Would a rose by another name smell as sweet? In European Review for Medical and Pharmacological Sciences, 24(5), 2781–83. [DOI:10.26355/eurrev_202003_20551] - DOI - PubMed

[8] Ceccarelli M., Berretta M., Venanzi Rullo E., Nunnari G., Cacopardo B. (2020). Differences and similarities between Severe Acute Respiratory Syndrome (SARS)-CoronaVirus (CoV) and SARS-CoV-2. Would a rose by another name smell as sweet? In European Review for Medical and Pharmacological Sciences, 24(5), 2781–83. [DOI:10.26355/eurrev_202003_20551] - DOI - PubMed

[9] Chen C., Zhang X. R., Ju Z. Y., He W. F. (2020). Advances in the research of cytokine storm mechanism induced by Corona Virus Disease 2019 and the corresponding immunotherapies. Zhonghua Shao Shang Za Zhi, 36(0), E005–E005. - PubMed

[10] Chen C., Zhang X. R., Ju Z. Y., He W. F. (2020). Advances in the research of cytokine storm mechanism induced by Corona Virus Disease 2019 and the corresponding immunotherapies. Zhonghua Shao Shang Za Zhi, 36(0), E005–E005. - PubMed

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COVID-19 and Central Nervous System: Entry Routes And

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COVID-19 and Central Nervous System: Entry Routes And

Authors

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Abstract

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