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. 2020 Aug 12;12(8):2420.
doi: 10.3390/nu12082420.

Effects of Consumption of Alcohol on Intraocular Pressure: Korea National Health and Nutrition Examination Survey 2010 to 2011

Ji Eun Song  1 , Joon Mo Kim  1 , Mi Yeon Lee  2 , Hye Joo Jang  1 , Ki Ho Park  3
Affiliations

Effects of Consumption of Alcohol on Intraocular Pressure: Korea National Health and Nutrition Examination Survey 2010 to 2011

Ji Eun Song et al. Nutrients. .

Abstract

This study researched the association between alcohol consumption, intraocular pressure (IOP), and risk of open-angle glaucoma (OAG) using nationwide population-based cross-sectional data from the Korean population based survey. Information on alcohol intake was obtained by questionnaire and comprehensive ophthalmic examinations were performed. Among a total of 6057 participants, the prevalence of OAG was 4.4% (6.0% for men and 3.0% for women). Multivariate adjusted models showed that alcohol consumption showed significant relationship with changes in IOP. In sex-stratified analyses, alcohol consumption more than 2 times per week was associated with increased IOP in men without OAG, while in women with OAG drinking alcohol more than 4 times per week was associated with increased IOP. This study showed significant differences between men and women without glaucoma who consumed alcohol more than four times per week (p-value: 0.03). Our results suggest that alcohol consumption is associated with risk of elevated IOP depending on sex and presence of glaucoma in Koreans. Therefore, patients who need to control IOP should consider the effects of alcohol consumption.

Keywords: IOP; Koreans; alcohol consumption; open-angle glaucoma; sex.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Difference in intraocular pressure (IOP) according to alcohol consumption in total subjects (n = 6504) (A), subjects with glaucoma (n = 288) (B), and without glaucoma (n = 6216) (C). Data are presented as mean values (95% confidence intervals). The mean IOPs of men in total (mean IOP (95% CI) (IOP); 14.45 (14.11–14.79), p-value; 0.048) and non-glaucoma group (mean IOP (95% CI); 14.3 (13.98–14.62), p-value; 0.03) who consumed alcohol over four times per week are significantly higher than those of women (mean IOP in total subjects (95% CI); 13.37 (12.65–14.09), mean IOP in non-glaucoma subjects (95% CI); 13.27 (12.55–14)). Asterisks indicate significant differences at p < 0.05.
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