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. 2020 Jul 28:13:469-476.
doi: 10.2147/IJGM.S251075. eCollection 2020.

Relationship Between Helicobacter pylori Infection, Serum Vitamin D3 Level and Spontaneous Abortion

Hadeel Abdulelah Ibrahim  1
Affiliations

Relationship Between Helicobacter pylori Infection, Serum Vitamin D3 Level and Spontaneous Abortion

Hadeel Abdulelah Ibrahim. Int J Gen Med. .

Abstract

Background: The effects of vitamin D3 (VD3) on pregnancy outcomes remain obscure. Thus, this study aims to investigate the relationship between maternal H. pylori infection, low VD3 level, and spontaneous abortion.

Methods: This research is conducted in Shahid Ali Qader Consultant Clinic in Sulaimaniyah city in which 100 women with a history of abortion and 100 women with no history of miscarriage were included. Serum detection of anti-H. pyloriIgG, IgA, and VD3 were done using enzyme-linked immunosorbent assay (ELISA) technique.

Results: The mean of VD3, H. pylori IgG, and IgAin patients and control group cases was determined and analyzed statistically.

Conclusion: H. pylori infection and VD3 play a significant role in early pregnancy loss. Blood group A and O are more prone to spontaneous abortion.

Keywords: ABO grouping; antibody detection; bacterial infection; miscarriage; vitamin deficiency.

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Conflict of interest statement

The author reports no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Shows CI % of vitamin D3 (ng/mL) for both cases and control groups which is highly significant (p ≤ 0.001) when compared.
Figure 2
Figure 2
Shows the gestational period at the time of abortion in women of the case group (weeks).
Figure 3
Figure 3
Shows the percentage of abortions in examined subjects.
See this image and copyright information in PMC

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Grants and funding

This research is self-funded and no grant was obtained for it.