Population genetics: past, present, and future

doi:10.1007/s00439-020-02208-5

Review

. 2021 Feb;140(2):231-240.

doi: 10.1007/s00439-020-02208-5. Epub 2020 Jul 18.

Population genetics: past, present, and future

Atsuko Okazaki^{1

2}, Satoru Yamazaki³, Ituro Inoue⁴, Jurg Ott⁵

Affiliations

¹ Intractable Disease Research Center, Juntendo University, Tokyo, Japan.
² Laboratory of Statistical Genetics, Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA.
³ Department of Molecular Pharmacology, National Cerebral and Cardiovascular Center, Osaka, Japan.
⁴ Division of the Human Genetics, National Institute of Genetics, Shizuoka, Japan.
⁵ Laboratory of Statistical Genetics, Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA. ott@rockefeller.edu.

PMID: 32683493
PMCID: PMC7368598
DOI: 10.1007/s00439-020-02208-5

Review

Population genetics: past, present, and future

Atsuko Okazaki et al. Hum Genet. 2021 Feb.

. 2021 Feb;140(2):231-240.

doi: 10.1007/s00439-020-02208-5. Epub 2020 Jul 18.

Authors

Atsuko Okazaki^{1

2}, Satoru Yamazaki³, Ituro Inoue⁴, Jurg Ott⁵

Affiliations

¹ Intractable Disease Research Center, Juntendo University, Tokyo, Japan.
² Laboratory of Statistical Genetics, Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA.
³ Department of Molecular Pharmacology, National Cerebral and Cardiovascular Center, Osaka, Japan.
⁴ Division of the Human Genetics, National Institute of Genetics, Shizuoka, Japan.
⁵ Laboratory of Statistical Genetics, Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA. ott@rockefeller.edu.

PMID: 32683493
PMCID: PMC7368598
DOI: 10.1007/s00439-020-02208-5

Abstract

We present selected topics of population genetics and molecular phylogeny. As several excellent review articles have been published and generally focus on European and American scientists, here, we emphasize contributions by Japanese researchers. Our review may also be seen as a belated 50-year celebration of Motoo Kimura's early seminal paper on the molecular clock, published in 1968.

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Conflict of interest statement

The authors declare no conflict of interest.

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References

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1. Bell SC, Mall MA, Gutierrez H, Macek M, Madge S, Davies JC, Burgel PR, Tullis E, Castanos C, Castellani C, Byrnes CA, Cathcart F, Chotirmall SH, Cosgriff R, Eichler I, Fajac I, Goss CH, Drevinek P, Farrell PM, Gravelle AM, Havermans T, Mayer-Hamblett N, Kashirskaya N, Kerem E, Mathew JL, McKone EF, Naehrlich L, Nasr SZ, Oates GR, O'Neill C, Pypops U, Raraigh KS, Rowe SM, Southern KW, Sivam S, Stephenson AL, Zampoli M, Ratjen F. The future of cystic fibrosis care: a global perspective. Lancet Respir Med. 2020;8:65–124. doi: 10.1016/S2213-2600(19)30337-6. - DOI - PMC - PubMed
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[1] Adachi J, Hasegawa M (1992) MOLPHY, programs for molecular phylogenetics. I, PROTML, maximum likelihood inference of protein phylogeny. Computer science monographs, no. 27. Institute of Statistical Mathematics, Tokyo, pp 1–14

[2] Adachi J, Hasegawa M (1992) MOLPHY, programs for molecular phylogenetics. I, PROTML, maximum likelihood inference of protein phylogeny. Computer science monographs, no. 27. Institute of Statistical Mathematics, Tokyo, pp 1–14

[3] Adachi J, Hasegawa M (1996) MOLPHY version 2.3: Programs for molecular phylogenetics based on maximum likelihood. Computer science monographs, no. 28. Institute of Statistical Mathematics, Tokyo, pp 1–150

[4] Adachi J, Hasegawa M (1996) MOLPHY version 2.3: Programs for molecular phylogenetics based on maximum likelihood. Computer science monographs, no. 28. Institute of Statistical Mathematics, Tokyo, pp 1–150

[5] Antonio ML, Gao Z, Moots HM, Lucci M, Candilio F, Sawyer S, Oberreiter V, Calderon D, Devitofranceschi K, Aikens RC, Aneli S, Bartoli F, Bedini A, Cheronet O, Cotter DJ, Fernandes DM, Gasperetti G, Grifoni R, Guidi A, La Pastina F, Loreti E, Manacorda D, Matullo G, Morretta S, Nava A, Fiocchi Nicolai V, Nomi F, Pavolini C, Pentiricci M, Pergola P, Piranomonte M, Schmidt R, Spinola G, Sperduti A, Rubini M, Bondioli L, Coppa A, Pinhasi R, Pritchard JK. Ancient Rome: a genetic crossroads of Europe and the Mediterranean. Science. 2019;366:708–714. doi: 10.1126/science.aay6826. - DOI - PMC - PubMed

[6] Antonio ML, Gao Z, Moots HM, Lucci M, Candilio F, Sawyer S, Oberreiter V, Calderon D, Devitofranceschi K, Aikens RC, Aneli S, Bartoli F, Bedini A, Cheronet O, Cotter DJ, Fernandes DM, Gasperetti G, Grifoni R, Guidi A, La Pastina F, Loreti E, Manacorda D, Matullo G, Morretta S, Nava A, Fiocchi Nicolai V, Nomi F, Pavolini C, Pentiricci M, Pergola P, Piranomonte M, Schmidt R, Spinola G, Sperduti A, Rubini M, Bondioli L, Coppa A, Pinhasi R, Pritchard JK. Ancient Rome: a genetic crossroads of Europe and the Mediterranean. Science. 2019;366:708–714. doi: 10.1126/science.aay6826. - DOI - PMC - PubMed

[7] Bell SC, Mall MA, Gutierrez H, Macek M, Madge S, Davies JC, Burgel PR, Tullis E, Castanos C, Castellani C, Byrnes CA, Cathcart F, Chotirmall SH, Cosgriff R, Eichler I, Fajac I, Goss CH, Drevinek P, Farrell PM, Gravelle AM, Havermans T, Mayer-Hamblett N, Kashirskaya N, Kerem E, Mathew JL, McKone EF, Naehrlich L, Nasr SZ, Oates GR, O'Neill C, Pypops U, Raraigh KS, Rowe SM, Southern KW, Sivam S, Stephenson AL, Zampoli M, Ratjen F. The future of cystic fibrosis care: a global perspective. Lancet Respir Med. 2020;8:65–124. doi: 10.1016/S2213-2600(19)30337-6. - DOI - PMC - PubMed

[8] Bell SC, Mall MA, Gutierrez H, Macek M, Madge S, Davies JC, Burgel PR, Tullis E, Castanos C, Castellani C, Byrnes CA, Cathcart F, Chotirmall SH, Cosgriff R, Eichler I, Fajac I, Goss CH, Drevinek P, Farrell PM, Gravelle AM, Havermans T, Mayer-Hamblett N, Kashirskaya N, Kerem E, Mathew JL, McKone EF, Naehrlich L, Nasr SZ, Oates GR, O'Neill C, Pypops U, Raraigh KS, Rowe SM, Southern KW, Sivam S, Stephenson AL, Zampoli M, Ratjen F. The future of cystic fibrosis care: a global perspective. Lancet Respir Med. 2020;8:65–124. doi: 10.1016/S2213-2600(19)30337-6. - DOI - PMC - PubMed

[9] Cann RL, Stoneking M, Wilson AC. Mitochondrial DNA and human evolution. Nature. 1987;325:31–36. - PubMed

[10] Cann RL, Stoneking M, Wilson AC. Mitochondrial DNA and human evolution. Nature. 1987;325:31–36. - PubMed

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Population genetics: past, present, and future

Affiliations

Population genetics: past, present, and future

Authors

Affiliations

Abstract

Conflict of interest statement

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Miscellaneous

Abstract

Conflict of interest statement

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References

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