Damaged: Elevated GFAP and UCH-L1 as the Black Flag of Brain Injury

doi:10.1016/j.resuscitation.2020.07.002

Editorial

. 2020 Sep:154:110-111.

doi: 10.1016/j.resuscitation.2020.07.002. Epub 2020 Jul 9.

Damaged: Elevated GFAP and UCH-L1 as the Black Flag of Brain Injury

Taylor N Anderson¹, Holly E Hinson²

Affiliations

¹ Oregon Health & Science University Portland, OR, United States.
² Oregon Health & Science University Portland, OR, United States. Electronic address: hinson@ohsu.edu.

PMID: 32652118
PMCID: PMC8101054
DOI: 10.1016/j.resuscitation.2020.07.002

Editorial

Damaged: Elevated GFAP and UCH-L1 as the Black Flag of Brain Injury

Taylor N Anderson et al. Resuscitation. 2020 Sep.

. 2020 Sep:154:110-111.

doi: 10.1016/j.resuscitation.2020.07.002. Epub 2020 Jul 9.

Authors

Taylor N Anderson¹, Holly E Hinson²

Affiliations

¹ Oregon Health & Science University Portland, OR, United States.
² Oregon Health & Science University Portland, OR, United States. Electronic address: hinson@ohsu.edu.

PMID: 32652118
PMCID: PMC8101054
DOI: 10.1016/j.resuscitation.2020.07.002

No abstract available

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Comment on

Serum GFAP and UCH-L1 for the prediction of neurological outcome in comatose cardiac arrest patients.
Ebner F, Moseby-Knappe M, Mattsson-Carlgren N, Lilja G, Dragancea I, Undén J, Friberg H, Erlinge D, Kjaergaard J, Hassager C, Wise MP, Kuiper M, Stammet P, Wanscher M, Horn J, Ullén S, Cronberg T, Nielsen N. Ebner F, et al. Resuscitation. 2020 Sep;154:61-68. doi: 10.1016/j.resuscitation.2020.05.016. Epub 2020 May 21. Resuscitation. 2020. PMID: 32445783

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References

1. Nolan JP, Soar J, Cariou A, Cronberg T, Moulaert VRM, Deakin CD, et al. European Resuscitation Council and European Society of Intensive Care Medicine Guidelines for Post-resuscitation Care 2015: Section 5 of the European Resuscitation Council Guidelines for Resuscitation 2015. Resuscitation 2015;95:202–22, doi:10.1016/j.resuscitation.2015.07.018. - DOI - PubMed
1. Wijdicks EFM, Hijdra A, Young GB, Bassetti CL, Wiebe S. Practice Parameter: Prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2006;67:203–10, doi:10.1212/01.wnl.0000227183.21314.cd. - DOI - PubMed
1. Streitberger KJ, Leithner C, Wattenberg M, Tonner PH, Hasslacher J, Joannidis M, et al. Neuron-Specific Enolase Predicts Poor Outcome After Cardiac Arrest and Targeted Temperature Management: A Multicenter Study on 1,053 Patients. Crit Care Med 2017;45:1145–51, doi:10.1097/CCM.0000000000002335. - DOI - PubMed
1. Thelin EP, Jeppsson E, Frostell A, Svensson M, Mondello S, Bellander B-M-M, et al. Utility of neuron-specific enolase in traumatic brain injury; relations to S100B levels, outcome, and extracranial injury severity. Crit Care 2016. 20:, doi:10.1186/s13054-016-1450-y. - DOI - PMC - PubMed
1. Johnsson P, Blomquist S, Luhrs C, Malmkvist G, Alling C, Solem JO, et al. Neuron-specific enolase increases in plasma during and immediately after extracorporeal circulation. Ann Thorac Surg 2000;69:750–4, doi: 10.1016/s0003-4975(99)01393-4. - DOI - PubMed

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[1] Nolan JP, Soar J, Cariou A, Cronberg T, Moulaert VRM, Deakin CD, et al. European Resuscitation Council and European Society of Intensive Care Medicine Guidelines for Post-resuscitation Care 2015: Section 5 of the European Resuscitation Council Guidelines for Resuscitation 2015. Resuscitation 2015;95:202–22, doi:10.1016/j.resuscitation.2015.07.018. - DOI - PubMed

[2] Nolan JP, Soar J, Cariou A, Cronberg T, Moulaert VRM, Deakin CD, et al. European Resuscitation Council and European Society of Intensive Care Medicine Guidelines for Post-resuscitation Care 2015: Section 5 of the European Resuscitation Council Guidelines for Resuscitation 2015. Resuscitation 2015;95:202–22, doi:10.1016/j.resuscitation.2015.07.018. - DOI - PubMed

[3] Wijdicks EFM, Hijdra A, Young GB, Bassetti CL, Wiebe S. Practice Parameter: Prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2006;67:203–10, doi:10.1212/01.wnl.0000227183.21314.cd. - DOI - PubMed

[4] Wijdicks EFM, Hijdra A, Young GB, Bassetti CL, Wiebe S. Practice Parameter: Prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2006;67:203–10, doi:10.1212/01.wnl.0000227183.21314.cd. - DOI - PubMed

[5] Streitberger KJ, Leithner C, Wattenberg M, Tonner PH, Hasslacher J, Joannidis M, et al. Neuron-Specific Enolase Predicts Poor Outcome After Cardiac Arrest and Targeted Temperature Management: A Multicenter Study on 1,053 Patients. Crit Care Med 2017;45:1145–51, doi:10.1097/CCM.0000000000002335. - DOI - PubMed

[6] Streitberger KJ, Leithner C, Wattenberg M, Tonner PH, Hasslacher J, Joannidis M, et al. Neuron-Specific Enolase Predicts Poor Outcome After Cardiac Arrest and Targeted Temperature Management: A Multicenter Study on 1,053 Patients. Crit Care Med 2017;45:1145–51, doi:10.1097/CCM.0000000000002335. - DOI - PubMed

[7] Thelin EP, Jeppsson E, Frostell A, Svensson M, Mondello S, Bellander B-M-M, et al. Utility of neuron-specific enolase in traumatic brain injury; relations to S100B levels, outcome, and extracranial injury severity. Crit Care 2016. 20:, doi:10.1186/s13054-016-1450-y. - DOI - PMC - PubMed

[8] Thelin EP, Jeppsson E, Frostell A, Svensson M, Mondello S, Bellander B-M-M, et al. Utility of neuron-specific enolase in traumatic brain injury; relations to S100B levels, outcome, and extracranial injury severity. Crit Care 2016. 20:, doi:10.1186/s13054-016-1450-y. - DOI - PMC - PubMed

[9] Johnsson P, Blomquist S, Luhrs C, Malmkvist G, Alling C, Solem JO, et al. Neuron-specific enolase increases in plasma during and immediately after extracorporeal circulation. Ann Thorac Surg 2000;69:750–4, doi: 10.1016/s0003-4975(99)01393-4. - DOI - PubMed

[10] Johnsson P, Blomquist S, Luhrs C, Malmkvist G, Alling C, Solem JO, et al. Neuron-specific enolase increases in plasma during and immediately after extracorporeal circulation. Ann Thorac Surg 2000;69:750–4, doi: 10.1016/s0003-4975(99)01393-4. - DOI - PubMed

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Damaged: Elevated GFAP and UCH-L1 as the Black Flag of Brain Injury

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Damaged: Elevated GFAP and UCH-L1 as the Black Flag of Brain Injury

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