Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020:2118:3-20.
doi: 10.1007/978-1-0716-0319-2_1.

Procedures for the Synthesis and Capping of Metal Nanoparticles

Claudia Gutiérrez-Wing  1 , J Jesús Velázquez-Salazar  2 , Miguel José-Yacamán  3
Affiliations
Review

Procedures for the Synthesis and Capping of Metal Nanoparticles

Claudia Gutiérrez-Wing et al. Methods Mol Biol. 2020.

Abstract

The increasing impact of metallic nanoparticles on life sciences has stimulated the development of new techniques and multiple improvements to the existing methods of manufacturing nanoparticles with tailored properties. Nanoparticles can be synthesized through a variety of physical and chemical methods. The choice of preparation procedure will depend on the physical and chemical characteristics required in the final product, such as size, dispersion, chemical miscibility, and optical properties, among others. Here we review basic practical procedures used for the preparation of protected and unprotected metallic nanoparticles and describe a number of experimental procedures based on colloidal chemistry methods. These include gold nanoparticle synthesis by reduction with trisodium citrate, ascorbic acid, or sugars in aqueous phase and nanoparticle passivation with alkanethiols, CTAB, or BSA. We also describe microwave-assisted synthesis, nanoparticle synthesis in ethylene glycol, and template-assisted synthesis with dendrimers, and, briefly, how to control nanoparticle shape (star-shaped and branched nanoparticles).

Keywords: Colloidal particles; Nanomaterials; Nanoparticles; Nanostructures synthesis; Nanotechnology; Passivated particles.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

LinkOut - more resources