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Review
. 2020 Feb 25;9(3):528.
doi: 10.3390/cells9030528.

13 Plus 1: A 30-Year Perspective on Microtubule-Based Motility in Dictyostelium

Michael P Koonce  1
Affiliations
Review

13 Plus 1: A 30-Year Perspective on Microtubule-Based Motility in Dictyostelium

Michael P Koonce. Cells. .

Abstract

Individual gene analyses of microtubule-based motor proteins in Dictyosteliumdiscoideum have provided a rough draft of its machinery for cytoplasmic organization and division. This review collates their activities and looks forward to what is next. A comprehensive approach that considers the collective actions of motors, how they balance rates and directions, and how they integrate with the actin cytoskeleton will be necessary for a complete understanding of cellular dynamics.

Keywords: Dictyostelium; cell motility; dynein; kinesin; microtubules.

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Conflict of interest statement

The author declares no conflict of interest. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, and in the decision to publish the results.

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