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doi: 10.1016/j.ccell.2020.01.008.
Circles with a Point: New Insights into Oncogenic Extrachromosomal DNA
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- PMID: 32049044
- DOI: 10.1016/j.ccell.2020.01.008
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Circles with a Point: New Insights into Oncogenic Extrachromosomal DNA
Cancer Cell.
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Free article
Abstract
For decades, scientists have observed small extrachromosomal DNA fragments in tumor cells, yet comprehensive examination of their structure and function has remained difficult. Three recent studies, published in Nature, Cell, and Nature Genetics, have now shed important light on the architecture, regulatory capacity, and oncogenic nature of tumor-associated extrachromosomal DNA.
Copyright © 2020 Elsevier Inc. All rights reserved.
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