Cholestatic liver injury induced by food additives, dietary supplements and parenteral nutrition
- PMID: 31884416
- DOI: 10.1016/j.envint.2019.105422
Cholestatic liver injury induced by food additives, dietary supplements and parenteral nutrition
Abstract
Cholestasis refers to the accumulation of toxic levels of bile acids in the liver due to defective bile secretion. This pathological situation can be triggered by drugs, but also by ingredients contained in food, food supplements and parenteral nutrition. This paper provides an overview of the current knowledge on cholestatic injury associated with such ingredients, with particular emphasis on the underlying mechanisms of toxicity.
Keywords: Cholestasis; Dietary supplements; Food additives; Herbal supplements; Parenteral nutrition.
Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.
Conflict of interest statement
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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