Advances in the mechanism of high copper diets in restraining pigs growth

doi:10.1111/jpn.13213

Review

. 2020 Mar;104(2):667-678.

doi: 10.1111/jpn.13213. Epub 2019 Dec 16.

Advances in the mechanism of high copper diets in restraining pigs growth

Yang Gao¹, Wenyan Yang^{1

2

3}, Dongsheng Che^{1

2

3}, Seidu Adams¹, Lianyu Yang^{1

2

3}

Affiliations

¹ College of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
² Jilin Provincial Key Lab of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, China.
³ Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun, China.

PMID: 31840317
DOI: 10.1111/jpn.13213

Review

Advances in the mechanism of high copper diets in restraining pigs growth

Yang Gao et al. J Anim Physiol Anim Nutr (Berl). 2020 Mar.

. 2020 Mar;104(2):667-678.

doi: 10.1111/jpn.13213. Epub 2019 Dec 16.

Authors

Yang Gao¹, Wenyan Yang^{1

2

3}, Dongsheng Che^{1

2

3}, Seidu Adams¹, Lianyu Yang^{1

2

3}

Affiliations

¹ College of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
² Jilin Provincial Key Lab of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, China.
³ Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun, China.

PMID: 31840317
DOI: 10.1111/jpn.13213

Abstract

High copper feed has been widely used as an inexpensive and highly effective feed additive to promote growth performance of pigs. However, long-term feeding of high copper feed may reduce the growth-promoting effects of copper, time-dependent accumulation of copper in animal tissues and organs, and copper toxicity thereby reducing the growth performance of pigs. Due to the widespread effects of high copper supplementation in animals' diets, the benefits and drawbacks of high copper feeding in pigs have been reported in several studies. Meanwhile, few of these studies have systematically described the mechanism by which high copper diets restrain pig growth. Therefore, to address the concerns and give a better understanding of the mechanism of high copper diet in restraining pig growth in different systems, this paper reviews the research progress of long-term supplementation of high copper on the growth of pigs and provides some suggestions and further research directions.

Keywords: growth; gut; high copper diet; mechanism; pig; restrain.

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References

REFERENCES

1. Adams, S., Che, D., Hailong, J., Zhao, B., Rui, H., Danquah, K., & Qin, G. (2019). Effects of pulverized oyster mushroom (Pleurotus ostreatus) on diarrhea incidence, growth performance, immunity, and microbial composition in piglets. Journal of the Science of Food and Agriculture, 99(7), 3616-3627. https://doi.org/10.1002/jsfa.9582
1. Alexandrova, A., Petrov, L., Georgieva, A., Kessiova, M., Tzvetanova, E., Kirkova, M., & Kukan, M. (2008). Effect of copper intoxication on rat liver proteasome activity: Relationship with oxidative stress. Journal of Biochemical and Molecular Toxicology, 22(5), 354-362. https://doi.org/10.1002/jbt.20248
1. Andersson, K. E. (2018). Oxidative stress and its possible relation to lower urinary tract functional pathology. BJU International, 121(4), 527-533. https://doi.org/10.1111/bju.14063
1. Arredondo, M., Uauy, R., & González, M. (2000). Regulation of copper uptake and transport in intestinal cell monolayers by acute and chronic copper exposure. Biochimica et Biophysica Acta, 1474(2), 169-176. https://doi.org/10.1016/s0304-4165(00)00015-5
1. Aviello, G., & Knaus, U. G. (2017). ROS in gastrointestinal inflammation: Rescue or sabotage? British Journal of Pharmacology, 174(12), 1704-1718. https://doi.org/10.1111/bph.13428

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[1] Adams, S., Che, D., Hailong, J., Zhao, B., Rui, H., Danquah, K., & Qin, G. (2019). Effects of pulverized oyster mushroom (Pleurotus ostreatus) on diarrhea incidence, growth performance, immunity, and microbial composition in piglets. Journal of the Science of Food and Agriculture, 99(7), 3616-3627. https://doi.org/10.1002/jsfa.9582

[2] Adams, S., Che, D., Hailong, J., Zhao, B., Rui, H., Danquah, K., & Qin, G. (2019). Effects of pulverized oyster mushroom (Pleurotus ostreatus) on diarrhea incidence, growth performance, immunity, and microbial composition in piglets. Journal of the Science of Food and Agriculture, 99(7), 3616-3627. https://doi.org/10.1002/jsfa.9582

[3] Alexandrova, A., Petrov, L., Georgieva, A., Kessiova, M., Tzvetanova, E., Kirkova, M., & Kukan, M. (2008). Effect of copper intoxication on rat liver proteasome activity: Relationship with oxidative stress. Journal of Biochemical and Molecular Toxicology, 22(5), 354-362. https://doi.org/10.1002/jbt.20248

[4] Alexandrova, A., Petrov, L., Georgieva, A., Kessiova, M., Tzvetanova, E., Kirkova, M., & Kukan, M. (2008). Effect of copper intoxication on rat liver proteasome activity: Relationship with oxidative stress. Journal of Biochemical and Molecular Toxicology, 22(5), 354-362. https://doi.org/10.1002/jbt.20248

[5] Andersson, K. E. (2018). Oxidative stress and its possible relation to lower urinary tract functional pathology. BJU International, 121(4), 527-533. https://doi.org/10.1111/bju.14063

[6] Andersson, K. E. (2018). Oxidative stress and its possible relation to lower urinary tract functional pathology. BJU International, 121(4), 527-533. https://doi.org/10.1111/bju.14063

[7] Arredondo, M., Uauy, R., & González, M. (2000). Regulation of copper uptake and transport in intestinal cell monolayers by acute and chronic copper exposure. Biochimica et Biophysica Acta, 1474(2), 169-176. https://doi.org/10.1016/s0304-4165(00)00015-5

[8] Arredondo, M., Uauy, R., & González, M. (2000). Regulation of copper uptake and transport in intestinal cell monolayers by acute and chronic copper exposure. Biochimica et Biophysica Acta, 1474(2), 169-176. https://doi.org/10.1016/s0304-4165(00)00015-5

[9] Aviello, G., & Knaus, U. G. (2017). ROS in gastrointestinal inflammation: Rescue or sabotage? British Journal of Pharmacology, 174(12), 1704-1718. https://doi.org/10.1111/bph.13428

[10] Aviello, G., & Knaus, U. G. (2017). ROS in gastrointestinal inflammation: Rescue or sabotage? British Journal of Pharmacology, 174(12), 1704-1718. https://doi.org/10.1111/bph.13428

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Advances in the mechanism of high copper diets in restraining pigs growth

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Advances in the mechanism of high copper diets in restraining pigs growth

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