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Review
. 2020 Jan;34(1):94-103.
doi: 10.1002/ptr.6519. Epub 2019 Nov 11.

Herbal medicines to the treatment of skin and soft tissue infections: advantages of the multi-targets action

Tatiane Roquete Amparo  1 , Janaína Brandão Seibert  2 , Paula Melo de Abreu Vieira  2   3 , Luiz Fernando Medeiros Teixeira  1 , Orlando David Henrique Dos Santos  1   2 , Gustavo Henrique Bianco de Souza  1   2
Affiliations
Review

Herbal medicines to the treatment of skin and soft tissue infections: advantages of the multi-targets action

Tatiane Roquete Amparo et al. Phytother Res. 2020 Jan.

Abstract

The research for new treatments of skin and soft tissue infections (SSTIs) is important due to their high prevalence and number of hospitalizations. The purpose of this review is to address the pathophysiology of SSTIs to highlight the advantages of herbal medicines to their treatment, showing examples of species and compounds with multi-targets action. SSTIs have a complex physiopathology involving the microorganism, as well as inflammation and difficult healing. Therefore, antimicrobial, anti-inflammatory, antioxidant and healing activities are an approach possible for their treatment. Herbal medicines have a wide diversity of biological compounds, mainly phenolic compounds that may act on different targets and also have synergism between them. Therefore, a single medicine may have the four key activities that allied allow eliminating the infection, control the inflammation process and accelerating the healing process, preventing complications with chronic infections.

Keywords: herbal medicines; multi-target; skin and soft tissue infections.

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