Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Feb;72(2):161-174.
doi: 10.1111/jphp.13185. Epub 2019 Nov 11.

Chemical constituents, experimental and clinical pharmacology of Rosa damascena: a literature review

Muhammad Akram  1 , Muhammad Riaz  2 , Naveed Munir  3 , Naheed Akhter  4 , Sadia Zafar  5 , Farhat Jabeen  6 , Mohammad Ali Shariati  7 , Naheed Akhtar  8 , Zarfishan Riaz  1 , Syed Hassan Altaf  1 , Muhammad Daniyal  9 , Rabia Zahid  1 , Fahad Said Khan  1
Affiliations
Review

Chemical constituents, experimental and clinical pharmacology of Rosa damascena: a literature review

Muhammad Akram et al. J Pharm Pharmacol. 2020 Feb.

Abstract

Context: Rosa damascena Mill. is prescribed for the management of chest and abdominal pain, constipation, digestive disorders, menstrual bleeding and liver ailments.

Objective: The current review compiles up to date and complete information of whole plant of R. damascena with particular emphasis on its numerous scientifically proved pharmacological effects, traditional and folk medicinal uses.

Key finding: The data on the pharmacological effects of R. damascena were collected from various databases such as PubMed, Wiley Online Library, Elsevier and Web of Science using the keywords like phytoconstituents, pharmacology, medicinal uses and biological activity of R. damascene. Rosa damascena has a wide spectrum of bio-pharmacological activity like antidepressant, hypoglycaemic, anti-inflammatory, analgesic, antioxidant and antimicrobial. The main ingredients of R. damascena essential oil responsible for pharmacological activity are geraniol and citronellol. Its uses have been widely accepted in traditional system of medicines for the management of numerous diseases of human beings in different dosage forms.

Summary: Rosa damascena has a significant place in traditional system of medicine. It is cost-effective and an important plant with curative application in contemporary medicine. Further studies on the characterization of chemical constituents and scientific basis of pharmacological activity of R. damascena should be carried out to evaluate its impact on traditional system of medicines. Large-scale preclinical and clinical trials will be beneficial in investigating the mechanism of the therapeutic potential of R. damascene to explore its uses in pharmaceutical industries.

Keywords: biological activity; medicinal activity; research study.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Kaul V et al. Damask rose and marigold: prospective industrial crops. J Med Arom Plant Sci 2000; 22: 313-318.
    1. Cai Y-Z et al. Phenolic antioxidants (hydrolyzable tannins, flavonols, and anthocyanins) identified by LC-ESI-MS and MALDI-QIT-TOF MS from Rosa chinensis flowers. J Agric Food Chem 2005; 53: 9940-9948.
    1. Nikbakht A et al. Micropropagation of damask rose (Rosa damascena Mill.) cvs Azaran and Ghamsar. Int J Agri Biol 2005; 7: 535-538.
    1. Gudin S. Rose: genetics and breeding. Plant Breed Rev 2000; 17: 159-190.
    1. Tosun I et al. Anaerobic digestion of residues from rose oil production. ISWA 2002 World Environmental Congress and Exhibition, 2002: 8-12.