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Review

. 2019 Oct 23;11(515):eaay6863.

doi: 10.1126/scitranslmed.aay6863.

Intratumoral CD8⁺ T cells with stem cell-like properties: Implications for cancer immunotherapy

Werner Held¹, Imran Siddiqui², Karin Schaeuble², Daniel E Speiser¹

Affiliations

Affiliations

¹ Department of Oncology, University of Lausanne, Ch. des Boveresses 155, CH-1066 Lausanne, Switzerland. werner.held@unil.ch daniel.speiser@unil.ch.
² Department of Oncology, University of Lausanne, Ch. des Boveresses 155, CH-1066 Lausanne, Switzerland.

PMID: 31645454
DOI: 10.1126/scitranslmed.aay6863

Review

Intratumoral CD8⁺ T cells with stem cell-like properties: Implications for cancer immunotherapy

Werner Held et al. Sci Transl Med. 2019.

. 2019 Oct 23;11(515):eaay6863.

doi: 10.1126/scitranslmed.aay6863.

Authors

Werner Held¹, Imran Siddiqui², Karin Schaeuble², Daniel E Speiser¹

Affiliations

¹ Department of Oncology, University of Lausanne, Ch. des Boveresses 155, CH-1066 Lausanne, Switzerland. werner.held@unil.ch daniel.speiser@unil.ch.
² Department of Oncology, University of Lausanne, Ch. des Boveresses 155, CH-1066 Lausanne, Switzerland.

PMID: 31645454
DOI: 10.1126/scitranslmed.aay6863

Abstract

Intratumoral PD-1⁺ TCF1⁺ CD8⁺ T cells with stem cell-like properties mediate cellular expansion and tumor control in response to immunotherapy.

Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

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