doi: 10.1128/iai.56.11.3004-3006.1988.
Role in vivo for gamma interferon in control of pneumonia caused by Chlamydia trachomatis in mice
Affiliations
- PMID: 3139569
- PMCID: PMC259686
- DOI: 10.1128/iai.56.11.3004-3006.1988
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Role in vivo for gamma interferon in control of pneumonia caused by Chlamydia trachomatis in mice
Infect Immun.
1988 Nov.
Abstract
In a model of pneumonia caused by murine Chlamydia trachomatis, depletion experiments with monoclonal antibody to gamma interferon (IFN-gamma) made mice more susceptible. Repletion experiments giving exogenous recombinant murine IFN-gamma were not consistently protective. IFN-gamma may be necessary but not sufficient in host defense against the organism.
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