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Review
. 2019 Aug;33(3):173-184.
doi: 10.1055/s-0039-1693019. Epub 2019 Aug 2.

Acellular Dermal Matrices: Applications in Plastic Surgery

Shahryar Tork  1 , Ryan C Jefferson  1 , Jeffrey E Janis  2
Affiliations
Review

Acellular Dermal Matrices: Applications in Plastic Surgery

Shahryar Tork et al. Semin Plast Surg. 2019 Aug.

Abstract

Modern advances in tissue engineering have transformed the plastic surgeon's management strategies across a wide variety of applications. Comprehension of the fundamentals of biologic constructs is critical to navigating the available armamentarium. It is essential that plastic surgeons become familiar with some of the existing methods for utilizing biologics as well as the advantages and limitations to their use. In this article, the authors describe the basic science of biologics with a focus on acellular dermal matrices (ADMs), and review the recent evidence behind their use for a variety of reconstructive and aesthetic purposes. The review is organized by system and examines the common indications, techniques, and outcomes pertaining to the application of ADMs in select anatomic areas. The final section briefly considers possible future directions for using biologics in plastic and reconstructive surgery.

Keywords: Biologics; acellular dermal matrix; plastic surgery; reconstructive surgery.

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Conflict of interest statement

Conflicts of Interest Dr. Janis has been a consultant for LifeCell, Bard, Daiichi Sankyo, Allergan, and Pacira in the last 12 months but has no active relationships currently. He also receives royalties from Thieme Publishing. RJ and ST have no disclosures.

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