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Comment
. 2020 Aug;69(8):1540-1542.
doi: 10.1136/gutjnl-2019-319391. Epub 2019 Jul 31.

Comparison of the incidence of colorectal cancer in young adults between the USA and Europe

Ting Wei #  1 , Peng Luo #  2 , Xiaoli Zhang #  1 , Weiliang Zhu #  1 , Jian Zhang  2
Affiliations
Comment

Comparison of the incidence of colorectal cancer in young adults between the USA and Europe

Ting Wei et al. Gut. 2020 Aug.
No abstract available

Keywords: colorectal cancer; europe; incidence; united states; young adult.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
(A) The APC in patients with CRC aged 20–29 years old in the USA is 4.3%. In Europe, the APC was 1.7% from 1990 to 2004 and 7.9% from 2005 to 2016. (B) The APC in patients with CRC aged 30–39 years old in the USA is 2.47%. The APC in Europe from 1990 to 2005 was 0.3%, with an annual increase of 4.9% from 2005 to 2016. (C): The APC in patients with CRC aged 40–49 years old in the USA was reduced by 1.5% between 1990 and 1994 but increased by an average of 1.8% per year from 1994 to 2016. In Europe, the APC decreased by 0.8% between 1990 and 2004 but increased by 1.6% per year thereafter. (D) The APC in patients with CRC aged 20–29 years old in the USA from 1990 to 2011 was 3.0% and was as high as 16.0% from 2011 to 2016. The APC in Europe was 2.7% from 1990 to 2005 and 9.3% from 2005 to 2016. (E) The APC in patients with colon cancer in the age group of 30–39 years in the USA was 1.5% from 1990 to 2013 and reached 10.3% from 2013 to 2016. The APC in Europe from 1990 to 2006 was 0.5%, and from 2005 to 2016, it was 6.4%. (F) The APC in patients with colon cancer aged 40–49 years in the USA decreased by 2.2% per year from 1990 to 1996 and increased by an average of 1.7% per year from 1999 to 2016. The APC in Europe from 1990 to 2004 was −1.3%, with an average annual rate of 1.6% from 2004 to 2016. (G) The incidence rates of rectal cancer in patients aged 20–29 years old in the USA and Europe are increasing by 3.3% and 3.5% per year, respectively. (H) The APC in rectal cancer in the USA among those aged 30–39 year is 3.03%, compared with 1.6% in Europe. (I) In the USA, rectal cancer in patients aged 40–49 years is increase at a rate of 2.8% per year, while the incidence in Europe remains stable. *: APC is significantly different from zero. ‘− yellow’ and ‘− orange’ line: APC in incidence rates in the USA, 1990–2016. ‘· yellow’ and ‘· orange’ dot: aged-adjusted rates in the USA. ‘− dark blue’ and ‘− light blue’ line: APC in incidence rates in Europe, 1990–2016. ‘· dark blue’ and “· light blue’ dot: aged-adjusted rates in Europe. APC, annual per cent change; CRC, colorectal cancer.
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References

    1. Vuik FER, Nieuwenburg SAV, Bardou M, et al. . Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years. Gut 2019. 10.1136/gutjnl-2018-317592. [Epub ahead of print: 16 May 2019]. - DOI - PMC - PubMed
    1. Siegel RL, Fedewa SA, Anderson WF, et al. . Colorectal cancer incidence patterns in the United States, 1974–2013. J Natl Cancer Inst 2017;109 10.1093/jnci/djw322 - DOI - PMC - PubMed
    1. Teng A, Lee DY, Cai J, et al. . Patterns and outcomes of colorectal cancer in adolescents and young adults. J Surg Res 2016;205:19–27. 10.1016/j.jss.2016.05.036 - DOI - PubMed
    1. Murphy CC, Wallace K, Sandler RS, et al. . Racial disparities in incidence of young-onset colorectal cancer and patient survival. Gastroenterology 2019;156:958–65. 10.1053/j.gastro.2018.11.060 - DOI - PMC - PubMed
    1. Murphy CC, Lund JL, Sandler RS. Young-onset colorectal cancer: earlier diagnoses or increasing disease burden? Gastroenterology 2017;152:1809–12. 10.1053/j.gastro.2017.04.030 - DOI - PMC - PubMed