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Review
. 2019 Jul 3:2019:7254534.
doi: 10.1155/2019/7254534. eCollection 2019.

The Physicochemical Properties of Graphene Nanocomposites Influence the Anticancer Effect

Wenbo Yang  1 , Xiangyu Deng  1 , Wei Huang  1 , Xiangcheng Qing  1 , Zengwu Shao  1
Affiliations
Review

The Physicochemical Properties of Graphene Nanocomposites Influence the Anticancer Effect

Wenbo Yang et al. J Oncol. .

Abstract

Graphene nanocomposite is an inorganic nanocomposite material, which has been widely used in the treatment of tumor at present due to its ability of drug loading, modifiability, photothermal effect, and photodynamic effect. However, the application of graphene nanocomposite is now limited due to the fact that the functions mentioned above are not well realized. This is mainly because people do not have a systematic understanding of the physical and chemical properties of GO nanomolecules, so that we cannot make full use of GO nanomolecules to make the most suitable materials for the use of medicine. Here, we are the first to discuss the influence of the physicochemical properties of graphene nanocomposite on the various functions related to their antitumor effects. The relationship between some important physicochemical properties of graphene nanocomposite such as diameter, shape, and surface chemistry and their functions related to antitumor effects was obtained through analysis, which provides evidence for the application of related materials in the future.

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Figures

Figure 1
Figure 1
The idea of this article.
Figure 2
Figure 2
The effect of the shape of the nanoparticles on their action.
Figure 3
Figure 3
The importance of appropriate nanoparticle size to the application of GO.
Figure 4
Figure 4
The structure of GO. In the picture, the black spheres represent carbon atoms, the red spheres represent oxygen atoms, and the green spheres represent hydrogen atoms.
Figure 5
Figure 5
GO-PEG causes unnecessary immune responses in the body.
Figure 6
Figure 6
The synthesis and drug loading of GO-FA-BSA.
See this image and copyright information in PMC

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