New Insights on Properties and Spatial Distributions of Skeletal Stem Cells

doi:10.1155/2019/9026729

Review

. 2019 Jun 3:2019:9026729.

doi: 10.1155/2019/9026729. eCollection 2019.

New Insights on Properties and Spatial Distributions of Skeletal Stem Cells

Jun-Qi Liu¹, Qi-Wen Li¹, Zhen Tan²

Affiliations

¹ State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
² Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

PMID: 31281389
PMCID: PMC6589297
DOI: 10.1155/2019/9026729

Review

New Insights on Properties and Spatial Distributions of Skeletal Stem Cells

Jun-Qi Liu et al. Stem Cells Int. 2019.

. 2019 Jun 3:2019:9026729.

doi: 10.1155/2019/9026729. eCollection 2019.

Authors

Jun-Qi Liu¹, Qi-Wen Li¹, Zhen Tan²

Affiliations

¹ State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
² Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

PMID: 31281389
PMCID: PMC6589297
DOI: 10.1155/2019/9026729

Abstract

Skeletal stem cells (SSCs) are postnatal self-renewing, multipotent, and skeletal lineage-committed progenitors that are capable of giving rise to cartilage, bone, and bone marrow stroma including marrow adipocytes and stromal cells in vitro and in an exogenous environment after transplantation in vivo. Identifying and isolating defined SSCs as well as illuminating their spatiotemporal properties contribute to our understating of skeletal biology and pathology. In this review, we revisit skeletal stem cells identified most recently and systematically discuss their origin and distributions.

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References

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[1] Manilay J. O., Zouali M. Tight relationships between B lymphocytes and the skeletal system. Trends in Molecular Medicine. 2014;20(7):405–412. doi: 10.1016/j.molmed.2014.03.003. - DOI - PubMed

[2] Manilay J. O., Zouali M. Tight relationships between B lymphocytes and the skeletal system. Trends in Molecular Medicine. 2014;20(7):405–412. doi: 10.1016/j.molmed.2014.03.003. - DOI - PubMed

[3] Riddle R. C., Clemens T. L. Bone cell bioenergetics and skeletal energy homeostasis. Physiological Reviews. 2017;97(2):667–698. doi: 10.1152/physrev.00022.2016. - DOI - PMC - PubMed

[4] Riddle R. C., Clemens T. L. Bone cell bioenergetics and skeletal energy homeostasis. Physiological Reviews. 2017;97(2):667–698. doi: 10.1152/physrev.00022.2016. - DOI - PMC - PubMed

[5] Watson E. C., Adams R. H. Biology of bone: the vasculature of the skeletal system. Cold Spring Harbor Perspectives in Medicine. 2018;8(7) doi: 10.1101/cshperspect.a031559. - DOI - PMC - PubMed

[6] Watson E. C., Adams R. H. Biology of bone: the vasculature of the skeletal system. Cold Spring Harbor Perspectives in Medicine. 2018;8(7) doi: 10.1101/cshperspect.a031559. - DOI - PMC - PubMed

[7] Edwards J. R., Mundy G. R. Advances in osteoclast biology: old findings and new insights from mouse models. Nature Reviews Rheumatology. 2011;7(4):235–243. doi: 10.1038/nrrheum.2011.23. - DOI - PubMed

[8] Edwards J. R., Mundy G. R. Advances in osteoclast biology: old findings and new insights from mouse models. Nature Reviews Rheumatology. 2011;7(4):235–243. doi: 10.1038/nrrheum.2011.23. - DOI - PubMed

[9] Harada S., Rodan G. A. Control of osteoblast function and regulation of bone mass. Nature. 2003;423(6937):349–355. doi: 10.1038/nature01660. - DOI - PubMed

[10] Harada S., Rodan G. A. Control of osteoblast function and regulation of bone mass. Nature. 2003;423(6937):349–355. doi: 10.1038/nature01660. - DOI - PubMed

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New Insights on Properties and Spatial Distributions of Skeletal Stem Cells

Affiliations

New Insights on Properties and Spatial Distributions of Skeletal Stem Cells

Authors

Affiliations

Abstract

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