How Unavoidable Are Analytical Treatment Interruptions in HIV Cure-Related Studies?
- PMID: 31264691
- PMCID: PMC6636248
- DOI: 10.1093/infdis/jiz222
How Unavoidable Are Analytical Treatment Interruptions in HIV Cure-Related Studies?
Abstract
In this discussion, 2 established researchers and clinical trialists debate their opposing views on the utility, benefits, and risks of the use of analytical interruption of antiretroviral therapy as a clinical trial end point and outcome measure in human studies seeking to induce remission of or eradicate human immunodeficiency virus infection.
Keywords: Analytical treatment interruption; antiretroviral therapy; viral outgrowth assay.
© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
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