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. 2019 Jul 2;220(220 Suppl 1):S24-S26.
doi: 10.1093/infdis/jiz222.

How Unavoidable Are Analytical Treatment Interruptions in HIV Cure-Related Studies?

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How Unavoidable Are Analytical Treatment Interruptions in HIV Cure-Related Studies?

David M Margolis et al. J Infect Dis. .

Abstract

In this discussion, 2 established researchers and clinical trialists debate their opposing views on the utility, benefits, and risks of the use of analytical interruption of antiretroviral therapy as a clinical trial end point and outcome measure in human studies seeking to induce remission of or eradicate human immunodeficiency virus infection.

Keywords: Analytical treatment interruption; antiretroviral therapy; viral outgrowth assay.

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