The roles of mitochondria-associated membranes in mitochondrial quality control under endoplasmic reticulum stress
- PMID: 31220526
- DOI: 10.1016/j.lfs.2019.116587
The roles of mitochondria-associated membranes in mitochondrial quality control under endoplasmic reticulum stress
Abstract
The endoplasmic reticulum (ER) and mitochondria are two important organelles in cells. Mitochondria-associated membranes (MAMs) are lipid raft-like domains formed in the ER membranes that are in close apposition to mitochondria. They play an important role in signal transmission between these two essential organelles. When cells are exposed to internal or external stressful stimuli, the ER will activate an adaptive response called the ER stress response, which has a significant effect on mitochondrial function. Mitochondrial quality control is an important mechanism to ensure the functional integrity of mitochondria and the effect of ER stress on mitochondrial quality control through MAMs is of great significance. Therefore, in this review, we introduce ER stress and mitochondrial quality control, and discuss how ER stress signals are transmitted to mitochondria through MAMs. We then review the important roles of MAMs in mitochondrial quality control under ER stress.
Keywords: Ca(2+); Endoplasmic reticulum stress; Mitochondria associated membranes; Mitochondrial quality control.
Copyright © 2019 Elsevier Inc. All rights reserved.
Similar articles
-
New functions of mitochondria associated membranes in cellular signaling.Biochim Biophys Acta. 2014 Oct;1843(10):2253-62. doi: 10.1016/j.bbamcr.2014.03.009. Epub 2014 Mar 15. Biochim Biophys Acta. 2014. PMID: 24642268 Review.
-
Endoplasmic Reticulum-Mitochondria Communication Through Ca2+ Signaling: The Importance of Mitochondria-Associated Membranes (MAMs).Adv Exp Med Biol. 2017;997:49-67. doi: 10.1007/978-981-10-4567-7_4. Adv Exp Med Biol. 2017. PMID: 28815521 Review.
-
Mitochondria-Associated Membranes and ER Stress.Curr Top Microbiol Immunol. 2018;414:73-102. doi: 10.1007/82_2017_2. Curr Top Microbiol Immunol. 2018. PMID: 28349285 Review.
-
Mitochondria, endoplasmic reticulum and innate immune dysfunction in mood disorders: Do Mitochondria-Associated Membranes (MAMs) play a role?Biochim Biophys Acta Mol Basis Dis. 2020 Jun 1;1866(6):165752. doi: 10.1016/j.bbadis.2020.165752. Epub 2020 Feb 29. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32119897 Review.
-
Potential Roles of Mitochondria-Associated ER Membranes (MAMs) in Traumatic Brain Injury.Cell Mol Neurobiol. 2017 Nov;37(8):1349-1357. doi: 10.1007/s10571-017-0484-2. Epub 2017 Mar 21. Cell Mol Neurobiol. 2017. PMID: 28324201 Review.
Cited by
-
Intricate subcellular journey of nanoparticles to the enigmatic domains of endoplasmic reticulum.Drug Deliv. 2023 Dec;30(1):2284684. doi: 10.1080/10717544.2023.2284684. Epub 2023 Nov 21. Drug Deliv. 2023. PMID: 37990530 Free PMC article. Review.
-
Mitochondria-Associated Endoplasmic Reticulum Membranes in the Pathogenesis of Type 2 Diabetes Mellitus.Front Cell Dev Biol. 2020 Oct 20;8:571554. doi: 10.3389/fcell.2020.571554. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33195204 Free PMC article. Review.
-
Advances in the mechanism and treatment of mitochondrial quality control involved in myocardial infarction.J Cell Mol Med. 2021 Aug;25(15):7110-7121. doi: 10.1111/jcmm.16744. Epub 2021 Jun 23. J Cell Mol Med. 2021. PMID: 34160885 Free PMC article. Review.
-
Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress.World J Gastroenterol. 2023 May 7;29(17):2616-2627. doi: 10.3748/wjg.v29.i17.2616. World J Gastroenterol. 2023. PMID: 37213406 Free PMC article.
-
The Role of the Effects of Endoplasmic Reticulum Stress on NLRP3 Inflammasome in Diabetes.Front Cell Dev Biol. 2021 Apr 14;9:663528. doi: 10.3389/fcell.2021.663528. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33937267 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
