Exosomes: An emerging factor in atherosclerosis
- PMID: 31078042
- DOI: 10.1016/j.biopha.2019.108951
Exosomes: An emerging factor in atherosclerosis
Erratum in
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Corrigendum to "Exosomes: An emerging factor in atherosclerosis" [Biomed. Pharmacother. 115 (2019) 108951].Biomed Pharmacother. 2019 Oct;118:109119. doi: 10.1016/j.biopha.2019.109119. Epub 2019 Jun 21. Biomed Pharmacother. 2019. PMID: 31230947 No abstract available.
Abstract
Atherosclerosis is the main reason for morbidity and death caused by cardiovascular disease which leads to approximately 20% of total death around the world. Exosomes secreted by the cells is a kind of extracellular vesicles with lipid bilayer structure, containing a variety of cell specific lipid, nucleic acid and protein, involved in intercellular communication, plays an important role in different physiological and pathological process. In recent years, with the deepening of research, the role of exosomes in cardiovascular diseases has received extensive attention. This review summarizes the roles of exosomes and exosome-derived from microRNAs, proteins and DNA as biomarkers in the development of atherosclerosis, and explores the mechanism of exosome-mediated intercellular crosstalk in atherosclerosis, providing potential roles for diagnosis and treatment.
Keywords: Atherosclerosis; Endothelial cell; Exosome; Extracellular vesicles; MicroRNA; Platelet; Vascular smooth muscle cell.
Copyright © 2019. Published by Elsevier Masson SAS.
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